Method of designing synthetic nucleic acid sequences for optimal protein expression in a host cell

Details for Australian Patent Application No. 2003228440 (hide)

Owner Walter Reed Army Institute of Research

Inventors Angov, Evelina; Kincaid, Randall L; Lyon, Jeffrey A

Agent Phillips Ormonde Fitzpatrick

Pub. Number AU-B-2003228440

PCT Number PCT/US03/10384

PCT Pub. Number WO2003/085114

Priority 60/369,741 01.04.02 US; 60/379,688 09.05.02 US; 60/425,719 12.11.02 US

Filing date 1 April 2003

Wipo publication date 20 October 2003

Acceptance publication date 2 October 2008

International Classifications

C12N 15/67 (2006.01) Mutation or genetic engineering - General methods for enhancing the expression

C07K 14/445 (2006.01) Peptides having more than 20 amino acids

C12N 1/21 (2006.01) Micro-organisms, e.g. protozoa - modified by introduction of foreign genetic material

C12N 15/30 (2006.01) Mutation or genetic engineering - Genes encoding protozoal proteins, e.g. from Plasmodium, Trypanosoma, Eimeria

C12P 21/02 (2006.01) Preparation of peptides or proteins - having a known sequence of two or more amino acids, e.g. glutathione

A61K 39/00 (2006.01) Medicinal preparations containing antigens or antibodies

Event Publications

14 August 2003 Complete Application Filed

  Priority application(s): 60/369,741 01.04.02 US; 60/379,688 09.05.02 US; 60/425,719 12.11.02 US

27 November 2003 Application Open to Public Inspection

  Published as AU-B-2003228440

2 October 2008 Application Accepted

  Published as AU-B-2003228440

29 January 2009 Standard Patent Sealed

28 October 2010 Application Lapsed, Refused Or Withdrawn, Patent Ceased or Expired

  This patent ceased under section 143(a), or Expired. Note that applications or patents shown as lapsed or ceased may be restored at a later date.

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