Sulfonyl-derivatives as novel inhibitors of histone deacetylase

Details for Australian Patent Application No. 2003218738 (hide)

Owner Janssen Pharmaceutica N.V.

Inventors Dyatkin, Alexey, Borisovich; Van Emelen, Kristof; De Winter, Hans, Louis, Jos; Meerpoel, Lieven; Poncelet, Virginie, Sophie; Verdonck, Marc, Gustaaf, Celine; Pilatte, Isabelle, Noelle, Constance; Arts, Janine; Van Brandt, Sven, Franciscus, Anna; Van heusden, Jimmy Arnold Viviane; Backx, Leo, Jacobus, Jozef

Agent Shelston IP

Pub. Number AU-B-2003218738

PCT Number PCT/EP03/02516

PCT Pub. Number WO2003/076422

Priority 60/420,989 24.10.02 US; 60/363,799 13.03.02 US

Filing date 11 March 2003

Wipo publication date 22 September 2003

Acceptance publication date 8 January 2009

International Classifications

C07D 295/22 (2006.01) Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms

A61K 31/495 (2006.01) - having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine

A61K 31/496 (2006.01) - Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene

A61K 31/497 (2006.01)

A61K 31/501 (2006.01) - not condensed and containing further heterocyclic rings

A61K 31/506 (2006.01) - not condensed and containing further heterocyclic rings

A61K 31/5377 (2006.01)

A61K 31/551 (2006.01) - having two nitrogens as ring hetero atoms, e.g. clozapine, dilazep

A61P 43/00 (2006.01) Drugs for specific purposes, not provided for in groups

C07D 207/28 (2006.01) Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom

C07D 213/82 (2006.01) Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

C07D 215/36 (2006.01) Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems

C07D 233/34 (2006.01) Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings

C07D 233/64 (2006.01) Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings

C07D 233/84 (2006.01) Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings

C07D 233/90 (2006.01) Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings

C07D 237/24 (2006.01) Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings

C07D 239/42 (2006.01) Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings

C07D 239/48 (2006.01) Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings

C07D 241/24 (2006.01) Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings

C07D 241/26 (2006.01) Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings

C07D 243/08 (2006.01) Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms

C07D 261/10 Heterocyclic compounds having nitrogen and oxygen as the only ring hetero atoms

Event Publications

31 July 2003 Complete Application Filed

  Priority application(s): 60/420,989 24.10.02 US; 60/363,799 13.03.02 US

30 October 2003 Application Open to Public Inspection

  Published as AU-B-2003218738

18 August 2005 Amendment Made

  The nature of the amendment is: Add co-inventor Van heusden, Jimmy Arnold Viviane

8 January 2009 Application Accepted

  Published as AU-B-2003218738

7 May 2009 Standard Patent Sealed

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