Substituted tetracycline compounds

Details for Australian Patent Application No. 2003218243 (hide)

Owner Paratek Pharmaceuticals, Inc.

Inventors Warchol, Tadeusz; Bandarage, Upul; Ohemeng, Kwasi; Pearson, Andre; Abato, Paul; Verma, Atul K.; Berniac, Joel; Honeyman, Laura; Frechette, Roger; Mechiche, Rachid; Bhatia, Beena; Viski, Peter; Amoo, Victor; Reddy, Laxma; Chen, Jackson; Nelson, Mark L.; Sheahan, Paul; Ismail, Mohamed Y.; Kim, Oak A.

Agent Watermark

Pub. Number AU-B-2003218243

PCT Number PCT/US03/08324

PCT Pub. Number WO2003/079984

Priority 60/367,048 21.03.02 US; 60/366,915 21.03.02 US; 60/367,045 21.03.02 US; 60/440,305 14.01.03 US; 60/395,468 12.07.02 US

Filing date 18 March 2003

Wipo publication date 8 October 2003

Acceptance publication date 1 April 2010

International Classifications

C07D 295/20 (2006.01) Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms

A61K 31/65 (2006.01) - Tetracyclines

A61P 31/04 (2006.01) Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics

A61P 43/00 (2006.01) Drugs for specific purposes, not provided for in groups

C07C 237/26 (2006.01) Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups

C07C 239/18 (2006.01) Compounds containing nitrogen-to-halogen bonds

C07C 245/20 (2006.01) Compounds containing chains of at least two nitrogen atoms with at least one nitrogen-to-nitrogen multiple bond

C07C 251/08 (2006.01) Compounds containing nitrogen atoms doubly- bound to a carbon skeleton

C07C 251/48 (2006.01) Compounds containing nitrogen atoms doubly- bound to a carbon skeleton

C07C 255/25 (2006.01) Carboxylic acid nitriles

C07C 255/43 (2006.01) Carboxylic acid nitriles

C07C 255/58 (2006.01) Carboxylic acid nitriles

C07C 255/59 (2006.01) Carboxylic acid nitriles

C07C 271/28 (2006.01) Derivatives of carbamic acid, i.e. compounds containing any of the groups the nitrogen atom not being part of nitro or nitroso groups

C07C 271/44 (2006.01) Derivatives of carbamic acid, i.e. compounds containing any of the groups the nitrogen atom not being part of nitro or nitroso groups

C07C 275/34 (2006.01) Derivatives of urea, i.e. compounds containing any of the groups the nitrogen atoms not being part of nitro or nitroso groups

C07C 279/18 (2006.01) Derivatives of guanidine, i.e. compounds containing the group the singly-bound nitrogen atoms not being part of nitro or nitroso groups

C07C 281/14 (2006.01) Derivatives of carbonic acid containing functional groups covered by groups in which at least one nitrogen atom of these functional groups is further bound to another nitrogen atom not being part of a nitro or nitroso group

C07C 309/61 (2006.01) Sulfonic acids

C07C 311/06 (2006.01) Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups

C07C 311/19 (2006.01) Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups

C07C 311/21 (2006.01) Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups

C07C 317/48 (2006.01) Sulfones

Event Publications

31 July 2003 Complete Application Filed

  Priority application(s): 60/367,048 21.03.02 US; 60/366,915 21.03.02 US; 60/367,045 21.03.02 US; 60/440,305 14.01.03 US; 60/395,468 12.07.02 US

13 November 2003 Application Open to Public Inspection

  Published as AU-B-2003218243

23 December 2004 Amendment Made

  The nature of the amendment is: Amend the names of the inventors to read Ismail, Mohamed Y, Bandarage, Upul, Kim, Oak A, Honeyman, Laura, Pearson, Andre, Reddy, Laxma, Sheahan, Paul, Verma, Atul K, Viski, Peter, Warchol, Tadeusz, Nelson, Mark L, Ohemeng, Kwasi, Frechette, Roger, Abato, Paul, Berniac, Joel, Bhatia, Beena and Chen, Jackson.

17 December 2009 Amendment Made

  The nature of the amendment is: Amend the name of the inventor to add co-inventors Amoo, Victor and Mechiche, Rachid

1 April 2010 Application Accepted

  Published as AU-B-2003218243

29 July 2010 Standard Patent Sealed

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