Improved prodrugs of CC-1065 analogs

Details for Australian Patent Application No. 2003218062 (hide)

Owner Immunogen, Inc.

Inventors Zhao, Robert Yongxin; Chari, Ravi V J

Agent Griffith Hack

Pub. Number AU-B-2003218062

PCT Number PCT/US03/07282

PCT Pub. Number WO2003/086318

Priority 10/116,053 05.04.02 US

Filing date 20 March 2003

Wipo publication date 27 October 2003

Acceptance publication date 23 August 2007

International Classifications

C07D 401/14 (2006.01) Heterocyclic compounds containing two or more hetero rings

A61K 31/404 (2006.01)

A61K 31/407 (2006.01) - condensed with heterocyclic ring systems, e.g. ketorolac, physostigmine

A61K 31/454 (2006.01)

A61K 31/4545 (2006.01)

A61K 31/496 (2006.01) - Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene

A61K 31/661 (2006.01) - Phosphorus acids or esters thereof not having PC bonds, e.g. fosfosal, dichlorvos, malathion

A61K 31/675 (2006.01) - having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate

A61K 47/48 (2006.01) Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives - the non-active ingredient being chemically bound to the active ingredient, e.g. polymer drug conjugates

A61P 35/00 (2006.01) Antineoplastic agents

A61P 43/00 (2006.01) Drugs for specific purposes, not provided for in groups

C07D 209/60 (2006.01) Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom

C07D 403/14 (2006.01) Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group

C07F 9/572 (2006.01) Compounds containing elements of the 5th Group of the Periodic System

C07F 9/6558 (2006.01) Compounds containing elements of the 5th Group of the Periodic System

Event Publications

31 July 2003 Complete Application Filed

  Priority application(s): 10/116,053 05.04.02 US

4 December 2003 Application Open to Public Inspection

  Published as AU-B-2003218062

23 August 2007 Application Accepted

  Published as AU-B-2003218062

20 December 2007 Standard Patent Sealed

26 June 2008 Alteration of Name

  The name of the patentee has been altered to ImmunoGen, Inc.

8 October 2009 Application for Amendment

  The nature of the amendment is as shown in the statement(s) filed 15 Sep 2009. Address for service in Australia - Griffith Hack 167 Eagle Street Brisbane QLD 4000

18 February 2010 Amendment Made

  The nature of the amendment is as shown in the statement(s) filed 15 Sep 2009

18 October 2012 Application Lapsed, Refused Or Withdrawn, Patent Ceased or Expired

  This patent ceased under section 143(a), or Expired. Note that applications or patents shown as lapsed or ceased may be restored at a later date.

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