Methods of preventing or treating disorders by administering an integrin alphavbeta3 antagonist in combination with an HMG-CoA reductase inhibitor or a bisphosphonate

Details for Australian Patent Application No. 2003213682 (hide)

Owner Medimmune, Inc.

Inventors Wilder, Ronald; Mao, Su-Yau

Agent Phillips Ormonde Fitzpatrick

Pub. Number AU-B-2003213682

PCT Number PCT/US03/06425

PCT Pub. Number WO2003/075741

Priority 60/361,859 04.03.02 US; 60/444,156 30.01.03 US; 60/370,398 05.04.02 US; 60/444,265 30.01.03 US

Filing date 4 March 2003

Wipo publication date 22 September 2003

Acceptance publication date 20 September 2007

International Classifications

A61K 45/00 (2006.01) Medicinal preparations containing active ingredients not provided for in groups

A61K 31/22 (2006.01)

A61K 31/366 (2006.01) - having six-membered rings, e.g. delta-lactones

A61K 31/40 (2006.01) - having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil

A61K 31/404 (2006.01)

A61K 31/4418 (2006.01) - having a carbocyclic ring directly attached to the heterocyclic ring, e.g. cyproheptadine

A61K 31/505 (2006.01) - Pyrimidines

A61K 31/565 (2006.01) - not substituted in position 17 beta by a carbon atom, e.g. oestrane, oestradiol

A61K 31/59 (2006.01) - Compounds containing 9,10-seco-cyclopenta[a]hydro- phenanthrene ring systems

A61K 31/663 (2006.01)

A61K 31/675 (2006.01) - having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate

A61K 38/23 (2006.01) Medicinal preparations containing peptides - Calcitonins

A61K 39/395 (2006.01) Medicinal preparations containing antigens or antibodies - Antibodies

A61K 45/06 (2006.01) Medicinal preparations containing active ingredients not provided for in groups

A61K 47/48 (2006.01) Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives - the non-active ingredient being chemically bound to the active ingredient, e.g. polymer drug conjugates

A61P 1/00 (2006.01) Drugs for disorders of the alimentary tract or the digestive system

A61P 1/02 (2006.01) Drugs for disorders of the alimentary tract or the digestive system

A61P 1/04 (2006.01) Drugs for disorders of the alimentary tract or the digestive system

A61P 3/10 (2006.01) Drugs for disorders of the metabolism

A61P 9/08 (2006.01) Drugs for disorders of the cardiovascular system

A61P 9/10 (2006.01) Drugs for disorders of the cardiovascular system

A61P 11/00 (2006.01) Drugs for disorders of the respiratory system

A61P 13/08 (2006.01) Drugs for disorders of the urinary system

A61P 15/00 Drugs for genital or sexual disorders

Event Publications

31 July 2003 Complete Application Filed

  Priority application(s): 60/361,859 04.03.02 US; 60/444,156 30.01.03 US; 60/370,398 05.04.02 US; 60/444,265 30.01.03 US

30 October 2003 Application Open to Public Inspection

  Published as AU-B-2003213682

20 September 2007 Application Accepted

  Published as AU-B-2003213682

13 December 2007 Application for Amendment

  The nature of the amendment is as shown in the statement(s) filed 18 Oct 2007. Address for service in Australia - Phillips Ormonde & Fitzpatrick Level 22 367 Collins Street Melbourne VIC 3000 2004

28 February 2008 Standard Patent Sealed

12 June 2008 Amendment Made

  The nature of the amendment is as shown in the statement(s) filed 18 Oct 2007

2 October 2008 Application Lapsed, Refused Or Withdrawn, Patent Ceased or Expired

  This patent ceased under section 143(a), or Expired. Note that applications or patents shown as lapsed or ceased may be restored at a later date.

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