Owner Genentech, Inc.

Inventors Godowski, Paul J; Gurney, Austin L; Goddard, Audrey; De Sauvage, Frederic J; Grimaldi, J Christopher; Wood, William I; Ghilardi, Nico P

Agent Griffith Hack

Pub. Number AU-B-2003213271

PCT Number PCT/US03/05616

PCT Pub. Number WO2003/072740

Priority 60/359,806 25.02.02 US

Filing date 24 February 2003

Wipo publication date 9 September 2003

Acceptance publication date 16 July 2009

C12N 15/09 (2006.01) Mutation or genetic engineering - Recombinant DNA-technology

A01K 67/027 (2006.01) Rearing or breeding animals, not otherwise provided for - New breeds of vertebrates

A61K 38/00 (2006.01) Medicinal preparations containing peptides

A61K 39/395 (2006.01) Medicinal preparations containing antigens or antibodies - Antibodies

A61K 45/00 (2006.01) Medicinal preparations containing active ingredients not provided for in groups

A61P 37/00 (2006.01) Drugs for immunological or allergic disorders

A61P 43/00 (2006.01) Drugs for specific purposes, not provided for in groups

C07K 14/715 (2006.01) Peptides having more than 20 amino acids

C07K 16/28 (2006.01) Immunoglobulins, e.g. monoclonal or polyclonal antibodies

C07K 16/46 (2006.01) Immunoglobulins, e.g. monoclonal or polyclonal antibodies - Hybrid immunoglobulins

C07K 19/00 (2006.01) Hybrid peptides

C12N 1/19 (2006.01) Micro-organisms, e.g. protozoa - modified by introduction of foreign genetic material

C12N 1/21 (2006.01) Micro-organisms, e.g. protozoa - modified by introduction of foreign genetic material

C12N 5/10 (2006.01) Undifferentiated human, animal or plant cells, e.g. cell lines - Cells modified by introduction of foreign genetic material, e.g. virus-transformed cells

C12N 15/00 (2006.01) Mutation or genetic engineering

C12P 21/02 (2006.01) Preparation of peptides or proteins - having a known sequence of two or more amino acids, e.g. glutathione

C12Q 1/02 (2006.01) Measuring or testing processes involving enzymes or micro-organisms - involving viable micro-organisms

G01N 33/15 (2006.01) Investigating or analysing materials by specific methods not covered by groups - Medicinal preparations

G01N 33/50 (2006.01) Investigating or analysing materials by specific methods not covered by groups - Chemical analysis of biological material, e.g. blood, urine

G01N 33/566 (2006.01) Investigating or analysing materials by specific methods not covered by groups - using specific carrier or receptor proteins as ligand binding reagent