Use of peptide-drug conjugation to reduce inter-subject variability of drug serum levels

Details for Australian Patent Application No. 2003213259 (hide)

Owner Shire LLC

Inventors Piccariello, Thomas; Kirk, Randal, J.

Agent FB Rice

Pub. Number AU-B-2003213259

PCT Number PCT/US03/05527

PCT Pub. Number WO2003/072735

Priority 60/358,382 22.02.02 US; 60/362,083 07.03.02 US

Filing date 24 February 2003

Wipo publication date 9 September 2003

Acceptance publication date 8 January 2009

International Classifications

A61K 38/22 (2006.01) Medicinal preparations containing peptides - Hormones

A61K 45/00 (2006.01) Medicinal preparations containing active ingredients not provided for in groups

A61K 47/48 (2006.01) Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives - the non-active ingredient being chemically bound to the active ingredient, e.g. polymer drug conjugates

A61P 5/14 (2006.01) Drugs for disorders of the endocrine system

C07K 5/06 (2006.01) Peptides having up to four amino acids in a fully defined sequence

Event Publications

24 July 2003 Complete Application Filed

  Priority application(s): 60/358,382 22.02.02 US; 60/362,083 07.03.02 US

16 October 2003 Application Open to Public Inspection

  Published as AU-B-2003213259

23 October 2003 Application Open to Public Inspection

  Published as AU-B-2003213259

24 January 2008 Assignment before Grant

  New River Pharmaceuticals Inc. The application has been assigned to Shire LLC

8 January 2009 Application Accepted

  Published as AU-B-2003213259

26 March 2009 Application for Amendment

  The nature of the amendment is as shown in the statement(s) filed 30 Jan 2009. Address for service in Australia - FB Rice & Co Level 23 200 Queen Street Melbourne VIC 3000

16 July 2009 Amendment Made

  The nature of the amendment is as shown in the statement(s) filed 30 Jan 2009

23 July 2009 Standard Patent Sealed

22 September 2011 Application Lapsed, Refused Or Withdrawn, Patent Ceased or Expired

  This patent ceased under section 143(a), or Expired. Note that applications or patents shown as lapsed or ceased may be restored at a later date.

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