Owner Rigel Pharmaceuticals, Inc.

Inventors Payan, Donald G; Sylvain, Catherine; Bhamidipati, Somasekhar; Li, Hui; Holland, Sacha J; Argade, Ankush; Rossi, Alexander B; Singh, Rajinder; Clough, Jeffrey; Molineaux, Susan; Keim, Holger

Agent Watermark

Pub. Number AU-B-2003208931

PCT Number PCT/US03/03022

PCT Pub. Number WO2003/063794

Priority 60/353,267 01.02.02 US; 60/434,277 17.12.02 US; 60/399,673 29.07.02 US; 60/353,333 01.02.02 US

Filing date 31 January 2003

Wipo publication date 2 September 2003

Acceptance publication date 4 September 2008

A61K 31/505 (2006.01) - Pyrimidines

A61K 31/506 (2006.01) - not condensed and containing further heterocyclic rings

A61K 31/519 (2006.01) - ortho- or peri-condensed with heterocyclic rings

A61K 31/5377 (2006.01)

A61P 1/00 (2006.01) Drugs for disorders of the alimentary tract or the digestive system

A61P 11/06 (2006.01) Drugs for disorders of the respiratory system

A61P 17/00 (2006.01) Drugs for dermatological disorders

A61P 27/02 (2006.01) Drugs for disorders of the senses

A61P 27/14 (2006.01) Drugs for disorders of the senses

A61P 27/16 (2006.01) Drugs for disorders of the senses

A61P 29/00 (2006.01) Non-central analgesic, antipyretic or antiinflammatory agents, e.g antirheumatic agents

A61P 37/08 (2006.01) Drugs for immunological or allergic disorders

A61P 43/00 (2006.01) Drugs for specific purposes, not provided for in groups

C07D 239/48 (2006.01) Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings

C07D 401/12 (2006.01) Heterocyclic compounds containing two or more hetero rings

C07D 401/14 (2006.01) Heterocyclic compounds containing two or more hetero rings

C07D 403/12 (2006.01) Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group

C07D 403/14 (2006.01) Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group

C07D 405/12 (2006.01) Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom

C07D 405/14 (2006.01) Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom

C07D 409/12 (2006.01) Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms

C07D 409/14 (2006.01) Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms

C07D 413/12 (2006.01) Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms