Pyrimidine A2B selective antagonist compounds, their synthesis and use

Details for Australian Patent Application No. 2002366811 (hide)

Owner OSI Pharmaceuticals, Inc.

Inventors Steinig, Arno; McKibben, Bryan; Collington, Eric William; Castelhano, Arlindo

Agent FB Rice

Pub. Number AU-B-2002366811

PCT Number PCT/US02/41273

PCT Pub. Number WO2003/053366

Priority 60/342,595 20.12.01 US

Filing date 20 December 2002

Wipo publication date 9 July 2003

Acceptance publication date 15 January 2009

International Classifications

C07D 243/08 (2006.01) Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms

A61K 31/506 (2006.01) - not condensed and containing further heterocyclic rings

A61K 31/513 (2006.01) - having oxo groups directly attached to the heterocyclic ring, e.g. cytosine

A61K 31/519 (2006.01) - ortho- or peri-condensed with heterocyclic rings

A61K 31/5377 (2006.01)

A61K 31/55 (2006.01) - having seven-membered rings, e.g. azelastine, pentylenetetrazole

A61K 31/551 (2006.01) - having two nitrogens as ring hetero atoms, e.g. clozapine, dilazep

A61P 1/00 (2006.01) Drugs for disorders of the alimentary tract or the digestive system

A61P 1/12 (2006.01) Drugs for disorders of the alimentary tract or the digestive system

A61P 3/10 (2006.01) Drugs for disorders of the metabolism

A61P 9/00 (2006.01) Drugs for disorders of the cardiovascular system

A61P 9/10 (2006.01) Drugs for disorders of the cardiovascular system

A61P 9/12 (2006.01) Drugs for disorders of the cardiovascular system

A61P 11/06 (2006.01) Drugs for disorders of the respiratory system

A61P 17/00 (2006.01) Drugs for dermatological disorders

A61P 17/04 (2006.01) Drugs for dermatological disorders

A61P 19/02 (2006.01) Drugs for skeletal disorders

A61P 27/02 (2006.01) Drugs for disorders of the senses

A61P 35/00 (2006.01) Antineoplastic agents

A61P 37/08 (2006.01) Drugs for immunological or allergic disorders

A61P 43/00 (2006.01) Drugs for specific purposes, not provided for in groups

C07D 239/42 (2006.01) Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings

C07D 239/48 (2006.01) Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings

C07D 401/12 Heterocyclic compounds containing two or more hetero rings

Event Publications

28 August 2003 Complete Application Filed

  Priority application(s): 60/342,595 20.12.01 US

2 October 2003 Application Open to Public Inspection

  Published as AU-B-2002366811

15 January 2009 Application Accepted

  Published as AU-B-2002366811

14 May 2009 Standard Patent Sealed

19 July 2012 Application Lapsed, Refused Or Withdrawn, Patent Ceased or Expired

  This patent ceased under section 143(a), or Expired. Note that applications or patents shown as lapsed or ceased may be restored at a later date.

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