Modulation of immunostimulatory properties of oligonucleotide-based compounds by optimal presentation of 5' ends

Details for Australian Patent Application No. 2002365141 (hide)

Owner Idera Pharmaceuticals, Inc.

Inventors Bhagat, Lakshmi; Kandimalla, Ekambar M; Yu, Dong; Agrawal, Sudhir

Agent Freehills

Pub. Number AU-B-2002365141

PCT Number PCT/US02/34247

PCT Pub. Number WO2003/057822

Priority 60/344,767 24.10.01 US

Filing date 24 October 2002

Wipo publication date 24 July 2003

Acceptance publication date 14 June 2007

International Classifications

A61K 38/00 (2006.01) Medicinal preparations containing peptides

A61K 31/7105 (2006.01) - Natural ribonucleic acids, i.e. containing only riboses attached to adenine, guanine, cytosine or uracil and having 3'-5' phosphodiester links

A61K 31/711 (2006.01) - Natural deoxyribonucleic acids, i.e. containing only 2'-deoxyriboses attached to adenine, guanine, cytosine or thymine and having 3'-5' phosphodiester links

A61K 31/7115 (2006.01) - Nucleic acids or oligonucleotides having modified bases, i.e. other than adenine, guanine, cytosine, uracil or thymine

A61K 31/712 (2006.01) - Nucleic acids or oligonucleotides having modified sugars, i.e. other than ribose or 2'-deoxyribose

A61K 31/7125 (2006.01) - Nucleic acids or oligonucleotides having modified internucleoside linkage, i.e. other than 3'-5' phosphodiesters

A61K 39/00 (2006.01) Medicinal preparations containing antigens or antibodies

A61P 11/00 (2006.01) Drugs for disorders of the respiratory system

A61P 11/06 (2006.01) Drugs for disorders of the respiratory system

A61P 35/00 (2006.01) Antineoplastic agents

A61P 37/02 (2006.01) Drugs for immunological or allergic disorders

A61P 37/04 (2006.01) Drugs for immunological or allergic disorders

A61P 37/08 (2006.01) Drugs for immunological or allergic disorders

C07H 21/00 (2006.01) Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids

C07H 21/02 (2006.01) Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids

C07H 21/04 (2006.01) Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids

C12N 15/11 (2006.01) Mutation or genetic engineering - DNA or RNA fragments

Event Publications

31 July 2003 Complete Application Filed

  Priority application(s): 60/344,767 24.10.01 US

4 September 2003 Application Open to Public Inspection

  Published as AU-B-2002365141

23 March 2006 Assignment before Grant

  Hybridon, Inc. The application has been assigned to Idera Pharmaceuticals, Inc.

14 June 2007 Application Accepted

  Published as AU-B-2002365141

18 October 2007 Standard Patent Sealed

13 March 2008 Application for Amendment

  The nature of the amendment is as shown in the statement(s) filed 11 Feb 2008. Address for service in Australia - Freehills Patent & Trade Mark Attorneys Level 43 101 Collins Street Mebourne VIC 3000 2003

24 July 2008 Amendment Made

  The nature of the amendment is as shown in the statement(s) filed 11 Feb 2008 2003

5 April 2012 Application for Amendment

  The nature of the amendment is as shown in the statement(s) filed 20 Mar 2012. Address for service in Australia - Freehills Patent & Trade Mark Attorneys Level 43 101 Collins Street Melbourne VIC 3000 2003

2 August 2012 Amendment Made

  The nature of the amendment is as shown in the statement(s) filed 20 Mar 2012 2004

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