Pyrimidine-based compounds useful as GSK-3 inhibitors

Details for Australian Patent Application No. 2002364536 (hide)

Owner Vertex Pharmaceuticals, Inc.

Inventors Davies, Robert J; Wannamaker, Marion W; Choquette, Deborah

Agent Davies Collison Cave

Pub. Number AU-B-2002364536

PCT Number PCT/US02/39190

PCT Pub. Number WO2003/049739

Priority 60/338,857 07.12.01 US

Filing date 9 December 2002

Wipo publication date 23 June 2003

Acceptance publication date 23 October 2008

International Classifications

A61K 31/506 (2006.01) - not condensed and containing further heterocyclic rings

A61K 31/517 (2006.01) - ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine

A61K 31/519 (2006.01) - ortho- or peri-condensed with heterocyclic rings

A61K 45/00 (2006.01) Medicinal preparations containing active ingredients not provided for in groups

A61P 3/00 (2006.01) Drugs for disorders of the metabolism

A61P 3/10 (2006.01) Drugs for disorders of the metabolism

A61P 9/00 (2006.01) Drugs for disorders of the cardiovascular system

A61P 9/10 (2006.01) Drugs for disorders of the cardiovascular system

A61P 11/06 (2006.01) Drugs for disorders of the respiratory system

A61P 17/14 (2006.01) Drugs for dermatological disorders

A61P 25/00 (2006.01) Drugs for disorders of the nervous system

A61P 25/14 (2006.01) Drugs for disorders of the nervous system

A61P 25/16 (2006.01) Drugs for disorders of the nervous system

A61P 25/18 (2006.01) Drugs for disorders of the nervous system

A61P 25/28 (2006.01) Drugs for disorders of the nervous system

A61P 29/00 (2006.01) Non-central analgesic, antipyretic or antiinflammatory agents, e.g antirheumatic agents

A61P 35/00 (2006.01) Antineoplastic agents

A61P 37/02 (2006.01) Drugs for immunological or allergic disorders

A61P 37/08 (2006.01) Drugs for immunological or allergic disorders

A61P 43/00 (2006.01) Drugs for specific purposes, not provided for in groups

C07D 239/94 (2006.01) Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings

C07D 401/12 (2006.01) Heterocyclic compounds containing two or more hetero rings

C07D 401/14 (2006.01) Heterocyclic compounds containing two or more hetero rings

C07D 403/12 Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group

Event Publications

17 July 2003 Complete Application Filed

  Priority application(s): 60/338,857 07.12.01 US

28 August 2003 Application Open to Public Inspection

  Published as AU-B-2002364536

4 May 2006 Application Lapsed, Refused Or Withdrawn, Patent Ceased or Expired

  This application lapsed under section 142(2)(a). A direction to request examination has been given for this application. Note that applications or patents shown as lapsed or ceased may be restored at a later date.

18 May 2006 Corrigenda

  Applications Lapsed, Refused or Withdrawn, Patents Ceased or Expired - 2002 Delete all reference to Application No. 2002364536

23 October 2008 Application Accepted

  Published as AU-B-2002364536

19 February 2009 Standard Patent Sealed

7 July 2011 Application Lapsed, Refused Or Withdrawn, Patent Ceased or Expired

  This patent ceased under section 143(a), or Expired. Note that applications or patents shown as lapsed or ceased may be restored at a later date.

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