Owner Iowa State University Research Foundation, Inc. Virginia Tech Intellectual Properties, Inc.

Inventors Meng, Xiang-Jin; Halbur, Patrick G; Fenaux, Martijn

Agent Phillips Ormonde Fitzpatrick

Pub. Number AU-B-2002362147

PCT Number PCT/US02/39646

PCT Pub. Number WO2003/049703

Priority 60/340,775 12.12.01 US; 10/314,512 09.12.02 US; 60/424,840 08.11.02 US

Filing date 11 December 2002

Wipo publication date 23 June 2003

Acceptance publication date 13 March 2008

C12N 15/09 (2006.01) Mutation or genetic engineering - Recombinant DNA-technology

A61K 35/76 (2006.01) Medicinal preparations containing material or reaction products thereof with undetermined constitution

A61K 38/00 (2006.01) Medicinal preparations containing peptides

A61K 39/12 (2006.01) Medicinal preparations containing antigens or antibodies - Viral antigens

A61K 48/00 (2006.01) Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases

A61P 31/20 (2006.01) Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics

A61P 43/00 (2006.01) Drugs for specific purposes, not provided for in groups

C07K 14/01 (2006.01) Peptides having more than 20 amino acids

C12N 1/15 (2006.01) Micro-organisms, e.g. protozoa - modified by introduction of foreign genetic material

C12N 1/19 (2006.01) Micro-organisms, e.g. protozoa - modified by introduction of foreign genetic material

C12N 1/21 (2006.01) Micro-organisms, e.g. protozoa - modified by introduction of foreign genetic material

C12N 5/10 (2006.01) Undifferentiated human, animal or plant cells, e.g. cell lines - Cells modified by introduction of foreign genetic material, e.g. virus-transformed cells

C12N 7/04 (2006.01) Viruses, e.g. bacteriophages - Inactivation or attenuation

C12P 21/02 (2006.01) Preparation of peptides or proteins - having a known sequence of two or more amino acids, e.g. glutathione