4-(benzylidene-amino)-3-(methylsulfany l)-4H-(1, 2, 4) triazin-5-one derivatives having a PDE-IV inhibiting and TNFantagonistic effect for the treatment of cardiac diseases and allergies

Details for Australian Patent Application No. 2002354850 (hide)

Owner Merck Patent GmbH

Inventors Leibrock, Joachim; Ehring, Thomas; Eggenweiler, Hans-Michael; Schelling, Pierre; Beier, Norbert; Wolf, Michael; Gassen, Michael

Agent Davies Collison Cave

Pub. Number AU-B-2002354850

PCT Number PCT/EP02/06742

PCT Pub. Number WO2003/008392

Priority 101 35 009.0 18.07.01 DE; 101 56 229.2 15.11.01 DE

Filing date 19 June 2002

Wipo publication date 3 March 2003

Acceptance publication date 28 February 2008

International Classifications

C07D 253/06 (2006.01) Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group

A61K 31/53 (2006.01) - having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine

A61P 1/04 (2006.01) Drugs for disorders of the alimentary tract or the digestive system

A61P 3/10 (2006.01) Drugs for disorders of the metabolism

A61P 7/00 (2006.01) Drugs for disorders of the blood or the extracellular fluid

A61P 9/04 (2006.01) Drugs for disorders of the cardiovascular system

A61P 9/10 (2006.01) Drugs for disorders of the cardiovascular system

A61P 11/00 (2006.01) Drugs for disorders of the respiratory system

A61P 11/06 (2006.01) Drugs for disorders of the respiratory system

A61P 17/00 (2006.01) Drugs for dermatological disorders

A61P 17/06 (2006.01) Drugs for dermatological disorders

A61P 19/02 (2006.01) Drugs for skeletal disorders

A61P 19/10 (2006.01) Drugs for skeletal disorders

A61P 25/00 (2006.01) Drugs for disorders of the nervous system

A61P 25/28 (2006.01) Drugs for disorders of the nervous system

A61P 29/00 (2006.01) Non-central analgesic, antipyretic or antiinflammatory agents, e.g antirheumatic agents

A61P 31/00 (2006.01) Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics

A61P 31/18 (2006.01) Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics

A61P 35/00 (2006.01) Antineoplastic agents

A61P 35/04 (2006.01) Antineoplastic agents

A61P 37/00 (2006.01) Drugs for immunological or allergic disorders

A61P 37/06 (2006.01) Drugs for immunological or allergic disorders

A61P 37/08 (2006.01) Drugs for immunological or allergic disorders

A61P 43/00 (2006.01) Drugs for specific purposes, not provided for in groups

Event Publications

20 March 2003 Complete Application Filed

  Priority application(s): 101 35 009.0 18.07.01 DE; 101 56 229.2 15.11.01 DE

22 May 2003 Application Open to Public Inspection

  Published as AU-B-2002354850

28 February 2008 Application Accepted

  Published as AU-B-2002354850

26 June 2008 Standard Patent Sealed

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