Owner The Government of the United States of America, represented by the Secretary, Department of Health and Human Services

Inventors Tsang, Kwong-yok; Schlom, Jeffrey

Agent Fisher Adams Kelly

Pub. Number AU-B-2002352913

PCT Number PCT/US02/37805

PCT Pub. Number WO2003/047506

Priority 60/334,575 30.11.01 US; 60/334,669 30.11.01 US

Filing date 26 November 2002

Wipo publication date 17 June 2003

Acceptance publication date 29 May 2008

G01N 33/50 (2006.01) Investigating or analysing materials by specific methods not covered by groups - Chemical analysis of biological material, e.g. blood, urine

A61K 31/7088 (2006.01) - Compounds having three or more nucleosides or nucleotides

A61K 35/12 (2006.01) Medicinal preparations containing material or reaction products thereof with undetermined constitution - Materials from mammals or birds

A61K 35/14 (2006.01) Medicinal preparations containing material or reaction products thereof with undetermined constitution - Blood

A61K 35/76 (2006.01) Medicinal preparations containing material or reaction products thereof with undetermined constitution

A61K 38/00 (2006.01) Medicinal preparations containing peptides

A61K 38/21 (2006.01) Medicinal preparations containing peptides - Interferons

A61K 39/39 (2006.01) Medicinal preparations containing antigens or antibodies - characterised by the immunostimulating additives, e.g. chemical adjuvants

A61K 48/00 (2006.01) Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases

A61P 13/08 (2006.01) Drugs for disorders of the urinary system

A61P 35/00 (2006.01) Antineoplastic agents

C07K 7/06 (2006.01) Peptides having 5 to 20 amino acids in a fully defined sequence

C07K 14/47 (2006.01) Peptides having more than 20 amino acids

C07K 16/18 (2006.01) Immunoglobulins, e.g. monoclonal or polyclonal antibodies - against material from animals or humans

C12N 5/10 (2006.01) Undifferentiated human, animal or plant cells, e.g. cell lines - Cells modified by introduction of foreign genetic material, e.g. virus-transformed cells

C12N 9/64 (2006.01) Enzymes, e.g. ligases (6.) - derived from animal tissue, e.g. rennin

C12N 15/09 (2006.01) Mutation or genetic engineering - Recombinant DNA-technology

C12P 21/02 (2006.01) Preparation of peptides or proteins - having a known sequence of two or more amino acids, e.g. glutathione

C12P 21/08 (2006.01) Preparation of peptides or proteins - Monoclonal antibodies

C12Q 1/02 (2006.01) Measuring or testing processes involving enzymes or micro-organisms - involving viable micro-organisms

C12Q 1/68 (2006.01) Measuring or testing processes involving enzymes or micro-organisms - involving nucleic acids

G01N 33/15 (2006.01) Investigating or analysing materials by specific methods not covered by groups - Medicinal preparations

G01N 33/53 (2006.01) Investigating or analysing materials by specific methods not covered by groups - Immunoassay

G01N 33/566 (2006.01) Investigating or analysing materials by specific methods not covered by groups - using specific carrier or receptor proteins as ligand binding reagent