Nucleic acid and amino acid sequences encoding high-level expressor factor VIII polypeptides and methods of use

Details for Australian Patent Application No. 2002337901 (hide)

Owner Expression Therapeutics LLC

Inventors Lollar, John S

Agent Pizzeys

Pub. Number AU-B-2002337901

PCT Number PCT/US02/33403

PCT Pub. Number WO2003/031598

Priority 60/327,388 05.10.01 US

Filing date 7 October 2002

Wipo publication date 22 April 2003

Acceptance publication date 17 January 2008

International Classifications

C12N 15/09 (2006.01) Mutation or genetic engineering - Recombinant DNA-technology

A61K 38/43 (2006.01) Medicinal preparations containing peptides - Enzymes

A61K 48/00 (2006.01) Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases

A61P 7/04 (2006.01) Drugs for disorders of the blood or the extracellular fluid

C07K 1/16 (2006.01) General processes for the preparation of peptides

C07K 14/755 (2006.01) Peptides having more than 20 amino acids

C12N 1/15 (2006.01) Micro-organisms, e.g. protozoa - modified by introduction of foreign genetic material

C12N 1/19 (2006.01) Micro-organisms, e.g. protozoa - modified by introduction of foreign genetic material

C12N 1/21 (2006.01) Micro-organisms, e.g. protozoa - modified by introduction of foreign genetic material

C12N 5/10 (2006.01) Undifferentiated human, animal or plant cells, e.g. cell lines - Cells modified by introduction of foreign genetic material, e.g. virus-transformed cells

C12P 21/02 (2006.01) Preparation of peptides or proteins - having a known sequence of two or more amino acids, e.g. glutathione

A61K 38/00 (2006.01) Medicinal preparations containing peptides

Event Publications

20 February 2003 Complete Application Filed

  Priority application(s): 60/327,388 05.10.01 US

3 July 2003 Application Open to Public Inspection

  Published as AU-B-2002337901

24 August 2006 Assignment before Grant

  Emory University The application has been assigned to Expression Therapeutics LLC

17 January 2008 Application Accepted

  Published as AU-B-2002337901

15 May 2008 Standard Patent Sealed

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