Owner MERCK AND CO., INC.

Inventors DININNO, Frank, P.; WU, Jane, Y.; KIM, Seongkon; CHEN, Helen, Y.

Pub. Number AU-A-2002335075

PCT Number PCT/US02/33258

PCT Pub. Number WO2003/086388

Priority 10/120,723 11.04.02 US

Filing date 11 October 2002

Wipo publication date 27 October 2003

A61K 031/395 - having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins

C07D 409/00 Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms

C07D 411/00 Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms

A61P 005/00 Drugs for disorders of the endocrine system

A61K 031/55 - having seven-membered rings, e.g. azelastine, pentylenetetrazole

A61K 031/445 - Non-condensed piperidines, e.g. piperocaine

A61K 031/40 - having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil

C07D 205/00 Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom

C07D 213/02 Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

C07D 405/00 Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom