Owner Isis Pharmaceuticals, Inc.

Inventors Freier, Susan M

Agent FB Rice

Pub. Number AU-B-2002334895

PCT Number PCT/US02/32060

PCT Pub. Number WO2003/030826

Priority 09/975,123 09.10.01 US

Filing date 7 October 2002

Wipo publication date 22 April 2003

Acceptance publication date 19 October 2006

C12N 15/11 (2006.01) Mutation or genetic engineering - DNA or RNA fragments

A61K 31/7088 (2006.01) - Compounds having three or more nucleosides or nucleotides

A61K 48/00 (2006.01) Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases

C07H 21/02 (2006.01) Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids

C07H 21/04 (2006.01) Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids

C12N 15/09 (2006.01) Mutation or genetic engineering - Recombinant DNA-technology

C12N 15/63 (2006.01) Mutation or genetic engineering - Introduction of foreign genetic material using vectors

C12P 19/34 (2006.01) Preparation of compounds containing saccharide radicals

C12Q 1/68 (2006.01) Measuring or testing processes involving enzymes or micro-organisms - involving nucleic acids