Protein based TNF-alpha variants for the treatment of TNF-alpha related disorders

Details for Australian Patent Application No. 2002334766 (hide)

Owner Xencor

Inventors Zalevsky, Jonathan; Dahiyat, Bassil I; Filikov, Anton; Muchhal, Umesh; Desjarlais, John R; Tansey, Malu

Agent Freehills

Pub. Number AU-B-2002334766

PCT Number PCT/US02/31277

PCT Pub. Number WO2003/033720

Priority 09/981,289 15.10.01 US

Filing date 30 September 2002

Wipo publication date 28 April 2003

Acceptance publication date 8 March 2007

International Classifications

C12N 15/09 (2006.01) Mutation or genetic engineering - Recombinant DNA-technology

A61K 38/22 (2006.01) Medicinal preparations containing peptides - Hormones

A61P 1/04 (2006.01) Drugs for disorders of the alimentary tract or the digestive system

A61P 17/06 (2006.01) Drugs for dermatological disorders

A61P 19/02 (2006.01) Drugs for skeletal disorders

A61P 25/00 (2006.01) Drugs for disorders of the nervous system

A61P 25/02 (2006.01) Drugs for disorders of the nervous system

A61P 29/00 (2006.01) Non-central analgesic, antipyretic or antiinflammatory agents, e.g antirheumatic agents

A61P 31/04 (2006.01) Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics

A61P 35/00 (2006.01) Antineoplastic agents

A61P 35/02 (2006.01) Antineoplastic agents

A61P 37/06 (2006.01) Drugs for immunological or allergic disorders

C07K 14/525 (2006.01) Peptides having more than 20 amino acids

C12N 1/15 (2006.01) Micro-organisms, e.g. protozoa - modified by introduction of foreign genetic material

C12N 1/19 (2006.01) Micro-organisms, e.g. protozoa - modified by introduction of foreign genetic material

C12N 1/21 (2006.01) Micro-organisms, e.g. protozoa - modified by introduction of foreign genetic material

C12N 5/10 (2006.01) Undifferentiated human, animal or plant cells, e.g. cell lines - Cells modified by introduction of foreign genetic material, e.g. virus-transformed cells

C12P 21/02 (2006.01) Preparation of peptides or proteins - having a known sequence of two or more amino acids, e.g. glutathione

A61K 38/00 (2006.01) Medicinal preparations containing peptides

Event Publications

13 February 2003 Complete Application Filed

  Priority application(s): 09/981,289 15.10.01 US

3 July 2003 Application Open to Public Inspection

  Published as AU-B-2002334766

8 March 2007 Application Accepted

  Published as AU-B-2002334766

6 September 2007 Standard Patent Sealed

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