Owner Eli Lilly and Company

Inventors Jamison, James Andrew; Hitchcock, Stephen Andrew; Allen, Jennifer Rebecca; Turner, William Wilson Jr; Liu, Bin

Agent Spruson & Ferguson

Pub. Number AU-B-2002332541

PCT Number PCT/US02/25969

PCT Pub. Number WO2003/027061

Priority 60/324,141 21.09.01 US

Filing date 9 September 2002

Wipo publication date 7 April 2003

Acceptance publication date 8 May 2008

C07D 333/38 (2006.01) Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom

A61K 31/166 (2006.01) - having the carbon atom of a carboxamide group directly attached to the aromatic ring, e.g. procainamide, procarbazine, metoclopramide, labetalol

A61K 31/341 (2006.01) - not condensed with another ring, e.g. ranitidine, furosemide, bufetolol, muscarine

A61K 31/381 (2006.01) - having five-membered rings

A61K 31/44 (2006.01) - Non-condensed pyridines

A61K 31/4436 (2006.01)

A61K 31/4965 (2006.01) - Non-condensed pyrazines

A61P 25/18 (2006.01) Drugs for disorders of the nervous system

A61P 25/28 (2006.01) Drugs for disorders of the nervous system

A61P 43/00 (2006.01) Drugs for specific purposes, not provided for in groups

C07C 257/14 (2006.01) Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines

C07D 207/325 (2006.01) Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom

C07D 213/54 (2006.01) Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

C07D 213/56 (2006.01) Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

C07D 213/81 (2006.01) Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

C07D 213/82 (2006.01) Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

C07D 213/84 (2006.01) Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

C07D 241/24 (2006.01) Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings

C07D 307/52 (2006.01) Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom

C07D 317/28 (2006.01) Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms

C07D 333/24 (2006.01) Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom

C07D 409/04 (2006.01) Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms