Owner Leo Pharma A/S

Inventors Horneman, Anne Marie; Liang, Xifu; Ottosen, Erik Rytter

Agent Callinan

Pub. Number AU-B-2002331310

PCT Number PCT/DK02/00557

PCT Pub. Number WO2003/018535

Priority 60/315,025 28.08.01 US; PA 2002 00189 08.02.02 DK

Filing date 26 August 2002

Wipo publication date 10 March 2003

Acceptance publication date 17 July 2008

C07D 295/12 (2006.01) Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms

A61K 31/135 (2006.01) - having aromatic rings, e.g. methadone

A61K 31/136 (2006.01) - having the amino group directly attached to the aromatic ring, e.g. benzeneamine

A61K 31/15 (2006.01) - Oximes (CNO)

A61K 31/165 (2006.01) - having aromatic rings, e.g. colchicine, atenolol, progabide

A61K 31/17 (2006.01) - having the group NC(O)N or NC(S)N, e.g. urea, thiourea, carmustine

A61K 31/221 (2006.01)

A61K 31/222 (2006.01)

A61K 31/277 (2006.01)

A61K 31/341 (2006.01) - not condensed with another ring, e.g. ranitidine, furosemide, bufetolol, muscarine

A61K 31/351 (2006.01) - not condensed with another ring

A61K 31/357 (2006.01) - having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel

A61K 31/4015 (2006.01) - having oxo groups directly attached to the heterocyclic ring, e.g. piracetam, ethosuximide

A61K 31/4035 (2006.01)

A61K 31/4166 (2006.01)

A61K 31/421 (2006.01) - 1,3-Oxazoles, e.g. pemoline, trimethadione

A61K 31/426 (2006.01) - 1,3-Thiazoles

A61K 31/445 (2006.01) - Non-condensed piperidines, e.g. piperocaine

A61K 31/495 (2006.01) - having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine

A61K 31/5375 (2006.01) - 1,4-Oxazines, e.g. morpholine

A61K 31/662 (2006.01) - Phosphorus acids or esters thereof having PC bonds, e.g. foscarnet, trichlorfon

A61K 31/7028 (2006.01) - Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages

A61P 1/04 Drugs for disorders of the alimentary tract or the digestive system