Prime ring substituted thyroid receptor antagonists for the treatment of cardiac and metabolic disorders

Details for Australian Patent Application No. 2002331145 (hide)

Owner Karo Bio AB

Inventors Sanin, Andrei; Koehler, Konrad; Brandt, Peter; Gordon, Sandra; Malm, Johan; Edvinsson, Karin

Agent Phillips Ormonde Fitzpatrick

Pub. Number AU-B-2002331145

PCT Number PCT/EP02/09120

PCT Pub. Number WO2003/018515

Priority 0120691.1 24.08.01 GB; 0207719.6 03.04.02 GB

Filing date 13 August 2002

Wipo publication date 10 March 2003

Acceptance publication date 10 July 2008

International Classifications

C07D 277/24 (2006.01) Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings

A61K 31/192 (2006.01)

A61K 31/195 (2006.01)

A61K 31/425 (2006.01) - Thiazoles

A61K 31/426 (2006.01) - 1,3-Thiazoles

A61K 31/44 (2006.01) - Non-condensed pyridines

A61K 31/496 (2006.01) - Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene

A61K 31/603 (2006.01)

A61P 1/16 (2006.01) Drugs for disorders of the alimentary tract or the digestive system

A61P 3/00 (2006.01) Drugs for disorders of the metabolism

A61P 5/14 (2006.01) Drugs for disorders of the endocrine system

A61P 9/00 (2006.01) Drugs for disorders of the cardiovascular system

A61P 9/06 (2006.01) Drugs for disorders of the cardiovascular system

A61P 17/00 (2006.01) Drugs for dermatological disorders

A61P 17/06 (2006.01) Drugs for dermatological disorders

A61P 37/08 (2006.01) Drugs for immunological or allergic disorders

A61P 43/00 (2006.01) Drugs for specific purposes, not provided for in groups

C07C 59/68 (2006.01) Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O-metal, CHO, keto, ether, groups, groups, or groups

C07C 65/24 (2006.01) Compounds having carboxyl groups bound to carbon atoms of six-membered aromatic rings and containing any of the groups OH, O-metal, CHO, keto, ether, groups, groups, or groups

C07C 65/26 (2006.01) Compounds having carboxyl groups bound to carbon atoms of six-membered aromatic rings and containing any of the groups OH, O-metal, CHO, keto, ether, groups, groups, or groups

C07D 213/30 (2006.01) Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

C07D 241/12 (2006.01) Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings

Event Publications

6 February 2003 Complete Application Filed

  Priority application(s): 0120691.1 24.08.01 GB; 0207719.6 03.04.02 GB

5 June 2003 Application Open to Public Inspection

  Published as AU-B-2002331145

10 July 2008 Application Accepted

  Published as AU-B-2002331145

6 November 2008 Standard Patent Sealed

10 March 2011 Application Lapsed, Refused Or Withdrawn, Patent Ceased or Expired

  This patent ceased under section 143(a), or Expired. Note that applications or patents shown as lapsed or ceased may be restored at a later date.

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