Owner The General Hospital Corporation

Inventors Fishman, Mark C; Rottbauer, Wolfgang

Agent Pizzeys

Pub. Number AU-B-2002330177

PCT Number PCT/US02/31234

PCT Pub. Number WO2003/028537

Priority 60/326,646 01.10.01 US

Filing date 1 October 2002

Wipo publication date 14 April 2003

Acceptance publication date 26 June 2008

A01K 67/027 (2006.01) Rearing or breeding animals, not otherwise provided for - New breeds of vertebrates

A61K 31/00 (2006.01)

A61K 31/70 (2006.01) - Carbohydrates

A61K 31/7088 (2006.01) - Compounds having three or more nucleosides or nucleotides

A61K 31/7105 (2006.01) - Natural ribonucleic acids, i.e. containing only riboses attached to adenine, guanine, cytosine or uracil and having 3'-5' phosphodiester links

A61K 38/17 (2006.01) Medicinal preparations containing peptides - from animals

A61K 45/00 (2006.01) Medicinal preparations containing active ingredients not provided for in groups

A61K 48/00 (2006.01) Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases

A61P 1/00 (2006.01) Drugs for disorders of the alimentary tract or the digestive system

A61P 1/04 (2006.01) Drugs for disorders of the alimentary tract or the digestive system

A61P 1/16 (2006.01) Drugs for disorders of the alimentary tract or the digestive system

A61P 1/18 (2006.01) Drugs for disorders of the alimentary tract or the digestive system

A61P 35/00 (2006.01) Antineoplastic agents

A61P 43/00 (2006.01) Drugs for specific purposes, not provided for in groups

C07H 21/04 (2006.01) Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids

C07K 14/46 (2006.01) Peptides having more than 20 amino acids

C07K 16/00 (2006.01) Immunoglobulins, e.g. monoclonal or polyclonal antibodies

C07K 16/18 (2006.01) Immunoglobulins, e.g. monoclonal or polyclonal antibodies - against material from animals or humans

C07K 16/26 (2006.01) Immunoglobulins, e.g. monoclonal or polyclonal antibodies

C12N 1/15 (2006.01) Micro-organisms, e.g. protozoa - modified by introduction of foreign genetic material

C12N 1/19 (2006.01) Micro-organisms, e.g. protozoa - modified by introduction of foreign genetic material

C12N 1/21 (2006.01) Micro-organisms, e.g. protozoa - modified by introduction of foreign genetic material

C12N 5/10 (2006.01) Undifferentiated human, animal or plant cells, e.g. cell lines - Cells modified by introduction of foreign genetic material, e.g. virus-transformed cells

C12N 9/00 (2006.01) Enzymes, e.g. ligases (6.)