New mandelic acid derivatives and their use as thrombin inhibitors

Details for Australian Patent Application No. 2002324410 (hide)

Owner AstraZeneca AB

Inventors Johansson, Anders; Svensson, Arne; Inghardt, Tord

Agent Davies Collison Cave

Pub. Number AU-B-2002324410

PCT Number PCT/SE02/01557

PCT Pub. Number WO2003/018551

Priority 0102921-4 30.08.01 SE; PCT/SE01/02657 30.11.01 SE

Filing date 30 August 2002

Wipo publication date 10 March 2003

Acceptance publication date 24 April 2008

International Classifications

C07D 205/04 (2006.01) Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom

A61K 31/397 (2006.01) - having four-membered rings, e.g. azetidine

A61P 7/02 (2006.01) Drugs for disorders of the blood or the extracellular fluid

C07C 45/00 (2006.01) Preparation of compounds having CO groups bound only to carbon or hydrogen atoms

C07C 45/29 (2006.01) Preparation of compounds having CO groups bound only to carbon or hydrogen atoms

C07C 45/51 (2006.01) Preparation of compounds having CO groups bound only to carbon or hydrogen atoms

C07C 45/67 (2006.01) Preparation of compounds having CO groups bound only to carbon or hydrogen atoms

C07C 45/71 (2006.01) Preparation of compounds having CO groups bound only to carbon or hydrogen atoms

C07C 47/575 (2006.01) Compounds having CHO groups

C07C 59/56 (2006.01) Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O-metal, CHO, keto, ether, groups, groups, or groups

C07C 59/64 (2006.01) Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O-metal, CHO, keto, ether, groups, groups, or groups

C07C 69/732 (2006.01) Esters of carboxylic acids

C07C 69/734 (2006.01) Esters of carboxylic acids

C07C 69/738 (2006.01) Esters of carboxylic acids

C07C 205/59 (2006.01) Compounds containing nitro groups bound to a carbon skeleton

C07D 207/16 (2006.01) Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom

C07D 213/34 (2006.01) Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

C07D 213/54 (2006.01) Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

C07D 239/28 (2006.01) Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings

C07D 261/08 (2006.01) Heterocyclic compounds having nitrogen and oxygen as the only ring hetero atoms

C07D 401/12 (2006.01) Heterocyclic compounds containing two or more hetero rings

C07D 403/12 (2006.01) Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group

C07D 413/12 (2006.01) Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms

Event Publications

16 January 2003 Complete Application Filed

  Priority application(s): 0102921-4 30.08.01 SE; PCT/SE01/02657 30.11.01 SE

5 June 2003 Application Open to Public Inspection

  Published as AU-B-2002324410

24 April 2008 Application Accepted

  Published as AU-B-2002324410

24 July 2008 Application for Amendment

  The nature of the amendment is: Amend the names of the co-inventors to remove Johansson, Anders and Svensson, Arne. Address for service in Australia - Davies Collison Cave Level 15 1 Nicholson Street Melbourne VIC 3000 2003

20 November 2008 Amendment Made

  The nature of the amendment is: Delete co-inventors Johansson, Anders and Svensson, Arne

27 November 2008 Standard Patent Sealed

29 March 2012 Application Lapsed, Refused Or Withdrawn, Patent Ceased or Expired

  This patent ceased under section 143(a), or Expired. Note that applications or patents shown as lapsed or ceased may be restored at a later date.

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