Owner The Trustees of the University of Pennsylvania

Inventors Zhuang, Zhi-Ping; Kung, Mei-Ping; Kung, Hank F.

Agent Houlihan2

Pub. Number AU-B-2002323417

PCT Number PCT/US02/27201

PCT Pub. Number WO2003/018070

Priority 60/314,658 27.08.01 US

Filing date 27 August 2002

Wipo publication date 10 March 2003

Acceptance publication date 15 May 2008

C07C 205/11 (2006.01) Compounds containing nitro groups bound to a carbon skeleton

A61K 31/055 (2006.01)

A61K 31/085 (2006.01)

A61K 31/10 (2006.01)

A61K 31/122 (2006.01) - having the oxygen atom directly attached to a ring, e.g. quinones, vitamin K, anthralin

A61K 31/136 (2006.01) - having the amino group directly attached to the aromatic ring, e.g. benzeneamine

A61K 31/222 (2006.01)

A61K 31/235 (2006.01)

A61K 31/275 (2006.01) - Nitriles

A61K 31/32 (2006.01)

A61K 31/341 (2006.01) - not condensed with another ring, e.g. ranitidine, furosemide, bufetolol, muscarine

A61K 31/37 (2006.01)

A61K 31/381 (2006.01) - having five-membered rings

A61K 31/4406 (2006.01) - only substituted in position 3, e.g. zimeldine

A61K 31/4409 (2006.01) - only substituted in position 4, e.g. isoniazid, iproniazid

A61K 31/555 (2006.01) - containing heavy metals, e.g. hemin, hematin, melarsoprol

A61K 51/00 (2006.01) Preparations containing radioactive substances for use in therapy or testing

A61K 51/04 (2006.01) Preparations containing radioactive substances for use in therapy or testing

A61P 25/28 (2006.01) Drugs for disorders of the nervous system

C07C 15/52 (2006.01) Cyclic hydrocarbons containing only six-membered aromatic rings as cyclic part

C07C 39/27 (2006.01) Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring

C07C 43/225 (2006.01) Ethers

C07C 205/06 (2006.01) Compounds containing nitro groups bound to a carbon skeleton