Owner The State of Oregon acting by and through the State Board of Higher Education on behalf of the University of Oregon University of Southern California University of Miami The Government of the United States of America as represented by the Secretary of the Department of Health and Human Services

Inventors Jones, Peter, A.; Marquez Victor, E.; Matsen, Cindy, B.; Greer, Sheldon, B.; Cheng, Jonathan; Selker, Eric, U.

Agent Griffith Hack

Pub. Number AU-B-2002322805

PCT Number PCT/US02/24223

PCT Pub. Number WO2003/012051

Priority 60/309,242 31.07.01 US; 60/311,435 10.08.01 US

Filing date 30 July 2002

Wipo publication date 17 February 2003

Acceptance publication date 8 November 2007

C12N 15/09 (2006.01) Mutation or genetic engineering - Recombinant DNA-technology

A61K 31/706 (2006.01)

A61K 31/7068 (2006.01)

A61K 45/00 (2006.01) Medicinal preparations containing active ingredients not provided for in groups

A61K 48/00 (2006.01) Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases

A61P 35/00 (2006.01) Antineoplastic agents

A61P 43/00 (2006.01) Drugs for specific purposes, not provided for in groups

C07H 19/06 (2006.01) Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical

C07H 19/067 (2006.01) Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical

C07H 21/00 (2006.01) Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids