Fluoropyrrolidines as dipeptidyl peptidase inhibitors

Details for Australian Patent Application No. 2002322344 (hide)

Owner SmithKline Beecham Corporation

Inventors Randhawa, Amarjit Sab; Reister, Steven Michael; Lenhard, James Martin; Haffner, Curt Dale; McDougald, Darryl Lynn

Agent Phillips Ormonde Fitzpatrick

Pub. Number AU-B-2002322344

PCT Number PCT/US02/20471

PCT Pub. Number WO2003/002531

Priority 60/301,333 27.06.01 US; 60/376,015 26.04.02 US

Filing date 26 June 2002

Wipo publication date 3 March 2003

Acceptance publication date 11 August 2005

International Classifications

C07D 207/16 Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom

A61P 003/10 Drugs for disorders of the metabolism

C07D 401/12 Heterocyclic compounds containing two or more hetero rings

C07D 409/12 Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms

C07D 413/12 Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms

C07D 401/06 Heterocyclic compounds containing two or more hetero rings

C07D 409/06 Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms

A61K 031/40 - having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil

A61K 031/4025 - not condensed and containing further heterocyclic rings, e.g. cromakalim

Event Publications

16 January 2003 Complete Application Filed

  Priority application(s): 60/301,333 27.06.01 US; 60/376,015 26.04.02 US

15 May 2003 Application Open to Public Inspection

  Published as AU-B-2002322344

11 August 2005 Application Accepted

  Published as AU-B-2002322344

15 September 2005 Application for Amendment

  The nature of the amendment is as shown in the statement(s) filed 16 Aug 2005. Address for service in Australia - Phillips Ormonde & Fitzpatrick Level 21 367 Collins Street Melbourne VIC 3000 2005

5 January 2006 Standard Patent Sealed

16 February 2006 Amendment Made

  The nature of the amendment is as shown in the statement(s) filed 16 Aug 2005 2003

28 January 2010 Application Lapsed, Refused Or Withdrawn, Patent Ceased or Expired

  This patent ceased under section 143(a), or Expired. Note that applications or patents shown as lapsed or ceased may be restored at a later date.

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