Owner Exelixis, Inc.

Inventors Francis-Lang, Helen; Funke, Roel, P.; Plowman, Gregory, D.; Belvin, Marcia; Li, Danxi; Friedman, Lori

Agent Davies Collison Cave

Pub. Number AU-B-2002320264

PCT Number PCT/US02/21112

PCT Pub. Number WO2002/099083

Priority 60/296,076 05.06.01 US; 60/357,253 15.02.02 US; 60/328,605 10.10.01 US

Filing date 2 June 2002

Wipo publication date 16 December 2002

Acceptance publication date 1 May 2008

C12Q 1/68 (2006.01) Measuring or testing processes involving enzymes or micro-organisms - involving nucleic acids

A61K 31/7088 (2006.01) - Compounds having three or more nucleosides or nucleotides

A61K 39/395 (2006.01) Medicinal preparations containing antigens or antibodies - Antibodies

A61K 45/00 (2006.01) Medicinal preparations containing active ingredients not provided for in groups

A61K 48/00 (2006.01) Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases

A61P 35/00 (2006.01) Antineoplastic agents

A61P 43/00 (2006.01) Drugs for specific purposes, not provided for in groups

C12N 5/06 (2006.01) Undifferentiated human, animal or plant cells, e.g. cell lines -

C12N 5/10 (2006.01) Undifferentiated human, animal or plant cells, e.g. cell lines - Cells modified by introduction of foreign genetic material, e.g. virus-transformed cells

C12N 15/09 (2006.01) Mutation or genetic engineering - Recombinant DNA-technology

C12Q 1/02 (2006.01) Measuring or testing processes involving enzymes or micro-organisms - involving viable micro-organisms

C12Q 1/42 (2006.01) Measuring or testing processes involving enzymes or micro-organisms - involving phosphatase

C12Q 1/48 (2006.01) Measuring or testing processes involving enzymes or micro-organisms - involving transferase

C12Q 1/527 (2006.01) Measuring or testing processes involving enzymes or micro-organisms - involving lyase

G01N 33/15 (2006.01) Investigating or analysing materials by specific methods not covered by groups - Medicinal preparations

G01N 33/50 (2006.01) Investigating or analysing materials by specific methods not covered by groups - Chemical analysis of biological material, e.g. blood, urine

G01N 33/53 (2006.01) Investigating or analysing materials by specific methods not covered by groups - Immunoassay

G01N 33/566 (2006.01) Investigating or analysing materials by specific methods not covered by groups - using specific carrier or receptor proteins as ligand binding reagent

G01N 33/573 (2006.01) Investigating or analysing materials by specific methods not covered by groups - for enzymes or isoenzymes

G01N 33/574 (2006.01) Investigating or analysing materials by specific methods not covered by groups - for cancer

G01N 33/68 (2006.01) Investigating or analysing materials by specific methods not covered by groups - involving proteins, peptides or amino acids