Variolin derivatives and their use as antitumor agents

Details for Australian Patent Application No. 2002317329 (hide)

Owner Pharma Mar, S.A.

Inventors Del pozo, Carlos; Cuevas, Carmen; Manzanares, Ignacio; Francesch, Andres; Gonzalez, Juan Jose; Morris, Jonathan Charles; Munt, Simon; Anderson, Regan James; Remuinan, Modesto

Agent Griffith Hack

Pub. Number AU-B-2002317329

PCT Number PCT/GB02/03197

PCT Pub. Number WO2003/006457

Priority 0116966.3 11.07.01 GB

Filing date 11 July 2002

Wipo publication date 29 January 2003

Acceptance publication date 2 October 2008

International Classifications

C07D 401/06 (2006.01) Heterocyclic compounds containing two or more hetero rings

A61K 31/519 (2006.01) - ortho- or peri-condensed with heterocyclic rings

A61K 31/53 (2006.01) - having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine

A61P 35/00 (2006.01) Antineoplastic agents

C07D 213/64 (2006.01) Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

C07D 213/78 (2006.01) Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

C07D 239/38 (2006.01) Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings

C07D 401/14 (2006.01) Heterocyclic compounds containing two or more hetero rings

C07D 409/14 (2006.01) Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms

C07D 471/06 (2006.01) Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups

C07D 471/14 (2006.01) Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups

C07D 471/22 (2006.01) Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups

Event Publications

9 January 2003 Complete Application Filed

  Priority application(s): 0116966.3 11.07.01 GB

22 May 2003 Application Open to Public Inspection

  Published as AU-B-2002317329

15 May 2008 Amendment Made

  The nature of the amendment is: Add the name of co-inventors to read Morris, Jonathan Charles and Anderson, Regan James

2 October 2008 Application Accepted

  Published as AU-B-2002317329

29 January 2009 Standard Patent Sealed

9 February 2012 Application Lapsed, Refused Or Withdrawn, Patent Ceased or Expired

  This patent ceased under section 143(a), or Expired. Note that applications or patents shown as lapsed or ceased may be restored at a later date.

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