Substituted naphthyl indole derivatives as inhibitors of plasminogen activator inhibitor type-1 (PAI-1)

Details for Australian Patent Application No. 2002316533 (hide)

Owner Wyeth

Inventors Elokdah, Hassan Mahmoud; Gundersen, Eric Gould; Crandall, David Leroy; Mayer, Scott Christian

Agent Phillips Ormonde Fitzpatrick

Pub. Number AU-B-2002316533

PCT Number PCT/US02/21113

PCT Pub. Number WO2003/000684

Priority 60/299,651 20.06.01 US

Filing date 18 June 2002

Wipo publication date 8 January 2003

Acceptance publication date 18 October 2007

International Classifications

C07D 403/12 (2006.01) Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group

A61K 31/404 (2006.01)

A61K 31/41 (2006.01) - having five-membered rings with two or more ring hetero atoms, at least one of which is nitrogen, e.g. tetrazole

A61P 3/04 (2006.01) Drugs for disorders of the metabolism

A61P 3/10 (2006.01) Drugs for disorders of the metabolism

A61P 7/02 (2006.01) Drugs for disorders of the blood or the extracellular fluid

A61P 9/04 (2006.01) Drugs for disorders of the cardiovascular system

A61P 9/06 (2006.01) Drugs for disorders of the cardiovascular system

A61P 9/10 (2006.01) Drugs for disorders of the cardiovascular system

A61P 9/12 (2006.01) Drugs for disorders of the cardiovascular system

A61P 11/06 (2006.01) Drugs for disorders of the respiratory system

A61P 13/12 (2006.01) Drugs for disorders of the urinary system

A61P 17/02 (2006.01) Drugs for dermatological disorders

A61P 17/06 (2006.01) Drugs for dermatological disorders

A61P 19/02 (2006.01) Drugs for skeletal disorders

A61P 19/10 (2006.01) Drugs for skeletal disorders

A61P 25/28 (2006.01) Drugs for disorders of the nervous system

A61P 29/00 (2006.01) Non-central analgesic, antipyretic or antiinflammatory agents, e.g antirheumatic agents

A61P 31/04 (2006.01) Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics

A61P 31/18 (2006.01) Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics

A61P 35/00 (2006.01) Antineoplastic agents

A61P 37/06 (2006.01) Drugs for immunological or allergic disorders

A61P 43/00 (2006.01) Drugs for specific purposes, not provided for in groups

C07D 209/12 (2006.01) Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom

Event Publications

9 January 2003 Complete Application Filed

  Priority application(s): 60/299,651 20.06.01 US

19 June 2003 Application Open to Public Inspection

  Published as AU-B-2002316533

18 October 2007 Application Accepted

  Published as AU-B-2002316533

14 February 2008 Standard Patent Sealed

14 January 2010 Application Lapsed, Refused Or Withdrawn, Patent Ceased or Expired

  This patent ceased under section 143(a), or Expired. Note that applications or patents shown as lapsed or ceased may be restored at a later date.

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