NOVEL NITRILES USEFUL AS REVERSIBLE INHIBITORS OF CYSTEINE PROTEASES

Details for Australian Patent Application No. 2002314898 (hide)

Owner BOEHRINGER INGELHEIM PHARMACEUTICALS, INC.

Inventors PATEL, Usha, R.; SPERO, Denice, M.; THOMSON, David, S.; YOUNG, Erick, R. R.; HICKEY, Eugene, R.; BEKKALI, Younes

Pub. Number AU-A-2002314898

PCT Number PCT/US02/17590

PCT Pub. Number WO2002/100849

Priority 60/296,863 08.06.01 US

Filing date 5 June 2002

Wipo publication date 23 December 2002

International Classifications

C07D 295/20 Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms

C07D 211/66 Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings

C07C 271/28 Derivatives of carbamic acid, i.e. compounds containing any of the groups the nitrogen atom not being part of nitro or nitroso groups

C07C 217/06 Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton

C07C 271/30 Derivatives of carbamic acid, i.e. compounds containing any of the groups the nitrogen atom not being part of nitro or nitroso groups

A61K 031/40 - having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil

A61K 031/435 - having six-membered rings with one nitrogen as the only ring hetero atom

A61K 031/275 - Nitriles

A61P 019/00 Drugs for skeletal disorders

A61P 009/00 Drugs for disorders of the cardiovascular system

A61P 037/00 Drugs for immunological or allergic disorders

A61P 025/00 Drugs for disorders of the nervous system

C07D 207/16 Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom

C07C 271/12 Derivatives of carbamic acid, i.e. compounds containing any of the groups the nitrogen atom not being part of nitro or nitroso groups

C07C 255/29 Carboxylic acid nitriles

C07C 271/34 Derivatives of carbamic acid, i.e. compounds containing any of the groups the nitrogen atom not being part of nitro or nitroso groups

Event Publications

2 January 2003 Complete Application Filed

  Priority application(s): 60/296,863 08.06.01 US

15 May 2003 Application Open to Public Inspection

  Published as AU-A-2002314898

11 March 2004 Application Lapsed, Refused Or Withdrawn, Patent Ceased or Expired

  This application lapsed under section 142(2)(f)/See Reg. 8.3(3). Examination has not yet been requested or directed for this application. Note that applications or patents shown as lapsed or ceased may be restored at a later date.

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