Owner Rhode Island Hospital

Inventors Wands, Jack R.; De La Monte, Suzanne M.

Agent Griffith Hack

Pub. Number AU-B-2002312033

PCT Number PCT/US02/16429

PCT Pub. Number WO2002/099036

Priority 09/872,968 01.06.01 US

Filing date 28 May 2002

Wipo publication date 16 December 2002

Acceptance publication date 18 October 2007

C12N 15/67 (2006.01) Mutation or genetic engineering - General methods for enhancing the expression

A01K 67/027 (2006.01) Rearing or breeding animals, not otherwise provided for - New breeds of vertebrates

A61K 9/127 (2006.01) Medicinal preparations characterised by special physical form - Liposomes

A61K 31/7088 (2006.01) - Compounds having three or more nucleosides or nucleotides

A61K 38/00 (2006.01) Medicinal preparations containing peptides

A61K 38/28 (2006.01) Medicinal preparations containing peptides - Insulins

A61K 39/395 (2006.01) Medicinal preparations containing antigens or antibodies - Antibodies

A61K 45/00 (2006.01) Medicinal preparations containing active ingredients not provided for in groups

A61K 47/24 (2006.01) Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives - containing atoms other than carbon, hydrogen, halogen, oxygen, nitrogen or sulfur

A61K 47/46 (2006.01) Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives - Ingredients of undetermined constitution or reaction products thereof

A61K 48/00 (2006.01) Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases

A61P 25/28 (2006.01) Drugs for disorders of the nervous system

C12N 5/08 (2006.01) Undifferentiated human, animal or plant cells, e.g. cell lines -

C12Q 1/02 (2006.01) Measuring or testing processes involving enzymes or micro-organisms - involving viable micro-organisms

G01N 33/15 (2006.01) Investigating or analysing materials by specific methods not covered by groups - Medicinal preparations

G01N 33/50 (2006.01) Investigating or analysing materials by specific methods not covered by groups - Chemical analysis of biological material, e.g. blood, urine