Owner The Scripps Research Institute

Inventors Pellequer, Jean-Luc; Gale, Andrew J.; Griffin, John H.; Getzoff, Elizabeth D.

Agent Shelston IP

Pub. Number AU-B-2002310438

PCT Number PCT/US02/19017

PCT Pub. Number WO2002/103024

Priority 60/298,578 14.06.01 US

Filing date 14 June 2002

Wipo publication date 2 January 2003

Acceptance publication date 1 May 2008

C12N 15/09 (2006.01) Mutation or genetic engineering - Recombinant DNA-technology

A61K 35/76 (2006.01) Medicinal preparations containing material or reaction products thereof with undetermined constitution

A61K 38/00 (2006.01) Medicinal preparations containing peptides

A61K 38/22 (2006.01) Medicinal preparations containing peptides - Hormones

A61K 38/48 (2006.01) Medicinal preparations containing peptides

A61K 48/00 (2006.01) Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases

A61P 7/04 (2006.01) Drugs for disorders of the blood or the extracellular fluid

C07K 1/107 (2006.01) General processes for the preparation of peptides

C07K 14/745 (2006.01) Peptides having more than 20 amino acids

C07K 14/755 (2006.01) Peptides having more than 20 amino acids

C12N 1/15 (2006.01) Micro-organisms, e.g. protozoa - modified by introduction of foreign genetic material

C12N 1/19 (2006.01) Micro-organisms, e.g. protozoa - modified by introduction of foreign genetic material

C12N 1/21 (2006.01) Micro-organisms, e.g. protozoa - modified by introduction of foreign genetic material

C12N 5/10 (2006.01) Undifferentiated human, animal or plant cells, e.g. cell lines - Cells modified by introduction of foreign genetic material, e.g. virus-transformed cells

C12N 9/64 (2006.01) Enzymes, e.g. ligases (6.) - derived from animal tissue, e.g. rennin

C12N 9/74 (2006.01) Enzymes, e.g. ligases (6.) - Thrombin

C12P 21/04 (2006.01) Preparation of peptides or proteins - Cyclic or bridged peptides or polypeptides, e.g. bacitracin