Cytotoxins, prodrugs, linkers and stabilizers useful therefor

Details for Australian Patent Application No. 2002303929 (hide)

Owner Medarex, Inc.

Inventors Ng, Howard P.; Boyd, Sharon; Moore, Jimmie; Li, Zhihong; McGee, Danny P. C.; Lobl, Thomas J.; Astafieva, Irina; Wu, Guoxian; Martichonok, Valeri; King, David J.; Saunders, Oliver L.; Yarranton, Geoffrey Thomas; Gangwar, Sanjeev

Agent Phillips Ormonde Fitzpatrick

Pub. Number AU-B-2002303929

PCT Number PCT/US02/17210

PCT Pub. Number WO2002/096910

Priority 60295342 31.05.01 US; 60295259 31.05.01 US; 60295196 31.05.01 US; 60304908 11.07.01 US

Filing date 31 May 2002

Wipo publication date 9 December 2002

Acceptance publication date 21 December 2006

International Classifications

C07D 487/04 (2006.01) Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups

A61K 31/343 (2006.01) - condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone

A61K 31/403 (2006.01) - condensed with carbocyclic rings, e.g. carbazole

A61K 31/407 (2006.01) - condensed with heterocyclic ring systems, e.g. ketorolac, physostigmine

A61K 31/4439 (2006.01)

A61K 31/454 (2006.01)

A61K 31/4545 (2006.01)

A61K 31/496 (2006.01) - Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene

A61K 38/00 (2006.01) Medicinal preparations containing peptides

A61K 39/395 (2006.01) Medicinal preparations containing antigens or antibodies - Antibodies

A61K 47/48 (2006.01) Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives - the non-active ingredient being chemically bound to the active ingredient, e.g. polymer drug conjugates

A61P 35/00 (2006.01) Antineoplastic agents

A61P 43/00 (2006.01) Drugs for specific purposes, not provided for in groups

C07D 405/06 (2006.01) Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom

C07D 405/12 (2006.01) Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom

C07D 405/14 (2006.01) Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom

C07D 487/10 (2006.01) Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups

C07F 7/18 (2006.01) Compounds containing elements of the 4th Group of the Periodic System

C07F 9/6561 (2006.01) Compounds containing elements of the 5th Group of the Periodic System

C07K 5/02 (2006.01) Peptides having up to four amino acids in a fully defined sequence

C07K 7/02 (2006.01) Peptides having 5 to 20 amino acids in a fully defined sequence

C07K 7/06 (2006.01) Peptides having 5 to 20 amino acids in a fully defined sequence

Event Publications

12 December 2002 Complete Application Filed

  Priority application(s): 60295342 31.05.01 US; 60295259 31.05.01 US; 60295196 31.05.01 US; 60304908 11.07.01 US

8 May 2003 Application Open to Public Inspection

  Published as AU-B-2002303929

27 November 2003 Assignment before Grant

  Coulter Pharmaceutical, Inc., A Wholly Owned Subsidiary of Corixa Corporation The application has been assigned to Medarex, Inc.

21 December 2006 Application Accepted

  Published as AU-B-2002303929

19 April 2007 Standard Patent Sealed

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