Owner Eli Lilly and Company

Inventors Miller, Shawn Christopher; Schaus, John Mehnert; Fisher, Matthew Joseph; McCowan, Jefferson Ray; Gillig, James Ronald; Chen, Zhaogen; Cohen, Michael Philip; Giethlen, Bruno

Agent Spruson & Ferguson

Pub. Number AU-B-2002303094

PCT Number PCT/US02/05115

PCT Pub. Number WO2002/078693

Priority 60/329,449 15.10.01 US; 60/279,928 29.03.01 US

Filing date 15 March 2002

Wipo publication date 15 October 2002

Acceptance publication date 23 November 2006

A61K 31/4045 (2006.01)

A61K 31/4402 (2006.01) - only substituted in position 2, e.g. pheniramine, bisacodyl

A61K 31/4406 (2006.01) - only substituted in position 3, e.g. zimeldine

A61K 31/4409 (2006.01) - only substituted in position 4, e.g. isoniazid, iproniazid

A61K 31/506 (2006.01) - not condensed and containing further heterocyclic rings

A61P 25/18 (2006.01) Drugs for disorders of the nervous system

A61P 25/28 (2006.01) Drugs for disorders of the nervous system

C07C 217/54 (2006.01) Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton

C07C 317/14 (2006.01) Sulfones

C07C 323/01 (2006.01) Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups

C07D 209/14 (2006.01) Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom

C07D 209/16 (2006.01) Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom

C07D 213/64 (2006.01) Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

C07D 233/24 (2006.01) Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings

C07D 239/34 (2006.01) Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings

C07D 277/34 (2006.01) Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings

C07D 307/91 (2006.01) Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom

C07D 333/20 (2006.01) Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom

C07D 401/12 (2006.01) Heterocyclic compounds containing two or more hetero rings

C07D 403/12 (2006.01) Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group