Owner BAUER, Shawn HUANG, Wenrong WOOLFREY, John SCARBOROUGH, Robert, M. MILLENNIUM PHARMACEUTICALS, INC. ZHU, Bin-Yan ZHANG, Penglie GOLDMAN, Erick, A. JIA, Zhaozhing, Jon

Inventors BAUER, Shawn; JIA, Zhaozhing, Jon; GOLDMAN, Erick, A.; ZHANG, Penglie; ZHU, Bin-Yan; SCARBOROUGH, Robert, M.; WOOLFREY, John; HUANG, Wenrong

Pub. Number AU-A-2002257112

PCT Pub. Number WO2002/079145

Priority 60/279,696 30.03.01 US

Filing date 1 April 2002

Wipo publication date 15 October 2002

C07C 257/18 Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines

C07C 279/18 Derivatives of guanidine, i.e. compounds containing the group the singly-bound nitrogen atoms not being part of nitro or nitroso groups

A61P 007/02 Drugs for disorders of the blood or the extracellular fluid

A61K 031/38 - having sulfur as a ring hetero atom

A61K 031/44 - Non-condensed pyridines

C07D 333/38 Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom

C07D 333/20 Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom

C07D 213/53 Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

C07D 213/46 Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members