Owner Pharmacia Corporation

Inventors Hassan, Fred; Huang, Tiehua; Brugger, Andrew M.; Bauer, Juliane M.; Karim, Aziz; Gao, Ping; Robins, Russell H.; Guido, Jane E.; Forbes, James C.

Agent Griffith Hack

Pub. Number AU-B-2002254609

PCT Pub. Number WO2002/102376

Priority 60/357,959 19.02.02 US; 60/284,589 17.04.01 US

Filing date 12 April 2002

Wipo publication date 2 January 2003

Acceptance publication date 21 June 2007

A61K 9/08 (2006.01) Medicinal preparations characterised by special physical form - Solutions

A61K 9/48 (2006.01) Medicinal preparations characterised by special physical form - Preparations in capsules, e.g. of gelatin, of chocolate

A61K 31/415 (2006.01) - 1,2-Diazoles

A61K 31/42 (2006.01) - Oxazoles

A61K 31/522 (2006.01)

A61K 31/635 (2006.01)

A61K 45/00 (2006.01) Medicinal preparations containing active ingredients not provided for in groups

A61K 45/06 (2006.01) Medicinal preparations containing active ingredients not provided for in groups

A61K 47/02 (2006.01) Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives - Inorganic compounds

A61K 47/04 (2006.01) Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives

A61K 47/10 (2006.01) Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives - Alcohols

A61K 47/12 (2006.01) Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives - Carboxylic acids

A61K 47/18 (2006.01) Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives

A61K 47/22 (2006.01) Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives - Heterocyclic compounds

A61K 47/34 (2006.01) Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives - Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds

A61K 47/38 (2006.01) Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives - Cellulose

A61K 47/48 (2006.01) Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives - the non-active ingredient being chemically bound to the active ingredient, e.g. polymer drug conjugates

A61P 25/06 (2006.01) Drugs for disorders of the nervous system

A61P 29/00 (2006.01) Non-central analgesic, antipyretic or antiinflammatory agents, e.g antirheumatic agents

A61P 43/00 (2006.01) Drugs for specific purposes, not provided for in groups

C07D 231/12 (2006.01) Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings

C07D 261/08 (2006.01) Heterocyclic compounds having nitrogen and oxygen as the only ring hetero atoms

C07D 413/12 (2006.01) Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms