Owner F. Hoffmann-La Roche AG

Inventors Lopez-Tapia, Francisco Javier; Nitzan, Dov; O'Yang, Counde

Agent Spruson & Ferguson

Pub. Number AU-B-2002253061

PCT Pub. Number WO2002/070500

Priority 60/272,872 02.03.01 US; 60/312,559 15.08.01 US

Filing date 25 February 2002

Wipo publication date 19 September 2002

Acceptance publication date 7 April 2005

C07D 307/80 Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom

C07C 271/28 Derivatives of carbamic acid, i.e. compounds containing any of the groups the nitrogen atom not being part of nitro or nitroso groups

C07D 239/26 Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings

A61K 031/34 - having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide

A61K 031/38 - having sulfur as a ring hetero atom

A61K 031/395 - having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins

A61K 031/41 - having five-membered rings with two or more ring hetero atoms, at least one of which is nitrogen, e.g. tetrazole

A61P 009/00 Drugs for disorders of the cardiovascular system

A61P 011/06 Drugs for disorders of the respiratory system

A61P 013/02 Drugs for disorders of the urinary system

A61P 029/00 Non-central analgesic, antipyretic or antiinflammatory agents, e.g antirheumatic agents

C07D 409/12 Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms

C07D 405/12 Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom

C07D 409/04 Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms

C07D 405/04 Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom