Owner Aventis Pharmaceuticals Inc

Inventors Urmann, Matthias; Bordeau, Kenneth J.; Angell, Paul; Jackson, Sharon Anne.; Hendrix, James A.; Chiang, Yulin; Strupczewski, Joseph T.; Fink, David M.; Collar, Nicola; Nieduzak, Thaddeus; Hemmerle, Horst; Sabuco, Jean-Francois; Jurcak, John G.; Shutske, Gregory

Agent Watermark

Pub. Number AU-B-2002250107

PCT Pub. Number WO2002/066446

Priority 0117577.7 19.07.01 GB; 60/269,672 16.02.01 US

Filing date 15 February 2002

Wipo publication date 4 September 2002

Acceptance publication date 29 May 2008

C07D 295/14 (2006.01) Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms

A61K 31/341 (2006.01) - not condensed with another ring, e.g. ranitidine, furosemide, bufetolol, muscarine

A61K 31/343 (2006.01) - condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone

A61K 31/352 (2006.01) - condensed with carbocyclic rings, e.g. cannabinols, methantheline

A61K 31/44 (2006.01) - Non-condensed pyridines

A61K 31/445 (2006.01) - Non-condensed piperidines, e.g. piperocaine

A61K 31/4525 (2006.01)

A61K 31/4535 (2006.01)

A61K 31/454 (2006.01)

A61K 31/46 (2006.01) - 8-Azabicyclo [3.2.1] octane

A61K 31/495 (2006.01) - having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine

A61K 31/496 (2006.01) - Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene

A61K 31/497 (2006.01)

A61K 31/506 (2006.01) - not condensed and containing further heterocyclic rings

A61K 31/535 (2006.01) - having six-membered rings with at least one nitrogen and at least one oxygen as the ring hetero atoms, e.g. 1,2-oxazines

A61K 31/5377 (2006.01)

A61K 31/551 (2006.01) - having two nitrogens as ring hetero atoms, e.g. clozapine, dilazep

A61K 45/00 (2006.01) Medicinal preparations containing active ingredients not provided for in groups

A61K 47/14 (2006.01) Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives - Esters of carboxylic acids

A61K 47/44 (2006.01) Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives - Oils, fats or waxes according to more than one of groups

A61K 51/00 (2006.01) Preparations containing radioactive substances for use in therapy or testing

A61P 25/14 (2006.01) Drugs for disorders of the nervous system

A61P 25/18 (2006.01) Drugs for disorders of the nervous system