Owner Baxter International Inc.

Inventors Brynjelsen, Sean; Rebbeck, Christine, L.; Kipp, James, E.; Wong, Joseph, Chung, Tak; Doty, Mark, J.; Werling, Jane; Sriram, Rajaram

Agent Peter Maxwell & Associates

Pub. Number AU-B-2002249836

PCT Pub. Number WO2002/055059

Priority 09/874,799 05.06.01 US; 10/035,821 19.10.01 US; 09/874,637 05.06.01 US; 10/021,692 12.12.01 US; 09/874,499 05.06.01 US; 60/258,160 22.12.00 US; 09/953,979 17.09.01 US

Filing date 20 December 2001

Wipo publication date 24 July 2002

Acceptance publication date 14 December 2006

C07D 407/14 (2006.01) Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group

A61K 9/10 (2006.01) Medicinal preparations characterised by special physical form - Dispersions

A61K 9/14 (2006.01) Medicinal preparations characterised by special physical form - Particulate form, e.g. powders

A61K 31/495 (2006.01) - having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine

A61K 31/496 (2006.01) - Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene

A61K 47/12 (2006.01) Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives - Carboxylic acids

A61K 47/14 (2006.01) Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives - Esters of carboxylic acids

A61K 47/18 (2006.01) Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives

A61K 47/20 (2006.01) Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives - containing sulfur

A61K 47/24 (2006.01) Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives - containing atoms other than carbon, hydrogen, halogen, oxygen, nitrogen or sulfur

A61K 47/28 (2006.01) Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives - Steroids

A61K 47/34 (2006.01) Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives - Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds

A61K 47/36 (2006.01) Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives - Polysaccharides

A61K 47/38 (2006.01) Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives - Cellulose

A61K 47/42 (2006.01) Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives - Proteins

A61P 31/10 (2006.01) Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics

A61K 9/16 (2006.01) Medicinal preparations characterised by special physical form - Agglomerates