Owner Rottapharm S.p.A.

Inventors Makovec, Francesco; Artusi, Roberto; Zanzola, Simona; Rovati, Lucio Claudio

Agent Phillips Ormonde Fitzpatrick

Pub. Number AU-B-2002249183

PCT Pub. Number WO2002/070468

Priority TO2001A000110 08.02.01 IT

Filing date 6 February 2002

Wipo publication date 19 September 2002

Acceptance publication date 16 November 2006

C07C 279/36 (2006.01) Derivatives of guanidine, i.e. compounds containing the group the singly-bound nitrogen atoms not being part of nitro or nitroso groups

A61K 31/155 (2006.01) - Amidines (), e.g. guanidine (HNC(NH)NH), isourea (HNC(OH)NH), isothiourea (HNC(SH)NH)

A61P 35/00 (2006.01) Antineoplastic agents

C07C 257/14 (2006.01) Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines

C07C 279/18 (2006.01) Derivatives of guanidine, i.e. compounds containing the group the singly-bound nitrogen atoms not being part of nitro or nitroso groups

C07C 335/20 (2006.01) Thioureas, i.e. compounds containing any of the groups the nitrogen atoms not being part of nitro or nitroso groups

C07D 209/18 (2006.01) Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom

C07D 209/42 (2006.01) Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom

C07D 213/40 (2006.01) Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members