Owner Medarex, Inc.

Inventors Hudson, Debra; Van Dijk, Marcus A.; Van De Winkel, Jan

Agent Shelston IP

Pub. Number AU-B-2002240338

PCT Pub. Number WO2002/064634

Priority 60/268,075 12.02.01 US; 60/338,956 05.11.01 US

Filing date 11 February 2002

Wipo publication date 28 August 2002

Acceptance publication date 27 October 2005

C07K 016/28 Immunoglobulins, e.g. monoclonal or polyclonal antibodies

G01N 033/68 Investigating or analysing materials by specific methods not covered by groups - involving proteins, peptides or amino acids

A61K 047/48 Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives - the non-active ingredient being chemically bound to the active ingredient, e.g. polymer drug conjugates

A61P 031/00 Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics

A61P 037/00 Drugs for immunological or allergic disorders

C07K 016/46 Immunoglobulins, e.g. monoclonal or polyclonal antibodies - Hybrid immunoglobulins

C12N 005/20 Undifferentiated human, animal or plant cells, e.g. cell lines - one of the fusion partners being a B lymphocyte

A01K 067/027 Rearing or breeding animals, not otherwise provided for - New breeds of vertebrates

C07K 019/00 Hybrid peptides

G01N 033/577 Investigating or analysing materials by specific methods not covered by groups - involving monoclonal antibodies

A61K 039/395 Medicinal preparations containing antigens or antibodies - Antibodies

C12N 015/79 Mutation or genetic engineering - Vectors or expression systems specially adapted for eukaryotic hosts