Owner Merck & Co., Inc.

Inventors Dininno, Frank P.; Wu, Jane Y.; Kim, Seongkon; Chen, Helen Y.

Agent Spruson & Ferguson

Pub. Number AU-B-2002232381

PCT Pub. Number WO02/32377

Priority 60241582 19.10.00 US

Filing date 15 October 2001

Wipo publication date 29 April 2002

Acceptance publication date 18 November 2004

A61K 031/395 - having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins

C07D 411/00 Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms

C07D 213/02 Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

C07D 205/00 Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom

C07D 409/00 Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms

C07D 405/00 Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom

A61P 005/00 Drugs for disorders of the endocrine system

A61K 031/40 - having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil

A61K 031/445 - Non-condensed piperidines, e.g. piperocaine

A61K 031/55 - having seven-membered rings, e.g. azelastine, pentylenetetrazole