Owner BTG International Limited

Inventors Koyama, Kazuo; Marumoto, Shinji; Toda, Narihiro; Kogen, Hiroshi; Suzuki, Keiko

Agent Davies Collison Cave

Pub. Number AU-B-2002226687

PCT Pub. Number WO2002/059074

Priority 2001-18386 26.01.01 JP; 2001-305182 01.10.01 JP

Filing date 22 January 2002

Wipo publication date 6 August 2002

Acceptance publication date 25 August 2005

C07C 219/22 Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton

C07D 217/16 Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems

C07D 223/16 Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom

A61K 031/27

A61K 031/36

A61K 031/4402 - only substituted in position 2, e.g. pheniramine, bisacodyl

A61K 031/4406 - only substituted in position 3, e.g. zimeldine

A61K 031/4409 - only substituted in position 4, e.g. isoniazid, iproniazid

A61K 031/44 - Non-condensed pyridines

A61K 031/381 - having five-membered rings

A61K 031/47 - Quinolines

A61K 031/472 - Non-condensed isoquinolines, e.g. papaverine

A61K 031/4035

A61K 031/55 - having seven-membered rings, e.g. azelastine, pentylenetetrazole

A61P 043/00 Drugs for specific purposes, not provided for in groups

A61P 025/28 Drugs for disorders of the nervous system

A61P 025/24 Drugs for disorders of the nervous system

A61P 025/14 Drugs for disorders of the nervous system

A61P 025/22 Drugs for disorders of the nervous system

C07C 271/44 Derivatives of carbamic acid, i.e. compounds containing any of the groups the nitrogen atom not being part of nitro or nitroso groups

C07C 321/28 Thiols, sulfides, hydropolysulfides or polysulfides

C07C 333/04 Derivatives of thiocarbamic acids, i.e. compounds containing any of the groups the nitrogen atom not being part of nitro or nitroso groups

C07D 317/58 Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms

C07D 317/64 Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms

C07D 213/64 Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

C07D 213/63 Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

C07D 333/32 Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom

C07D 333/40 Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom

C07D 215/20 Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems

C07D 209/44 Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom

C07D 217/14 Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems