Phenylalanine enamide derivatives possessing a cyclobutene group, for use as integrin inhibitors

Details for Australian Patent Application No. 2002225163 (hide)

Owner Celltech R&D Limited

Inventors Porter, John Robert; Brand, Stephen; Bailey, Stuart; Johnson, James Andrew; Head, John Clifford; Brown, Julien Alistair

Agent Freehills

Pub. Number AU-B-2002225163

PCT Pub. Number WO2002/068393

Priority 0114000.3 08.06.01 GB; 0127562.7 16.11.01 GB; 0104418.9 22.02.01 GB

Filing date 18 January 2002

Wipo publication date 12 September 2002

Acceptance publication date 2 August 2007

International Classifications

C07D 213/81 (2006.01) Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

A61K 31/198 (2006.01)

A61K 31/4375 (2006.01)

A61K 31/44 (2006.01) - Non-condensed pyridines

A61K 31/4406 (2006.01) - only substituted in position 3, e.g. zimeldine

A61K 31/497 (2006.01)

A61P 3/10 (2006.01) Drugs for disorders of the metabolism

A61P 9/00 (2006.01) Drugs for disorders of the cardiovascular system

A61P 17/00 (2006.01) Drugs for dermatological disorders

A61P 17/06 (2006.01) Drugs for dermatological disorders

A61P 19/02 (2006.01) Drugs for skeletal disorders

A61P 25/00 (2006.01) Drugs for disorders of the nervous system

A61P 29/00 (2006.01) Non-central analgesic, antipyretic or antiinflammatory agents, e.g antirheumatic agents

A61P 37/00 (2006.01) Drugs for immunological or allergic disorders

A61P 37/06 (2006.01) Drugs for immunological or allergic disorders

A61P 43/00 (2006.01) Drugs for specific purposes, not provided for in groups

C07C 229/34 (2006.01) Compounds containing amino and carboxyl groups bound to the same carbon skeleton

C07C 229/46 (2006.01) Compounds containing amino and carboxyl groups bound to the same carbon skeleton

C07C 233/82 (2006.01) Carboxylic acid amides

C07C 321/22 (2006.01) Thiols, sulfides, hydropolysulfides or polysulfides

C07C 323/30 (2006.01) Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups

C07D 213/89 (2006.01) Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

C07D 401/12 (2006.01) Heterocyclic compounds containing two or more hetero rings

Event Publications

6 March 2003 Application Open to Public Inspection

  Published as AU-B-2002225163

2 August 2007 Application Accepted

  Published as AU-B-2002225163

29 November 2007 Standard Patent Sealed

6 March 2008 Assignment Registered

  Celltech R&D Limited The patent has been assigned to UCB Pharma S.A.

11 August 2011 Application Lapsed, Refused Or Withdrawn, Patent Ceased or Expired

  This patent ceased under section 143(a), or Expired. Note that applications or patents shown as lapsed or ceased may be restored at a later date.

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