Owner Amgen Inc. Amgen Canada Inc.

Inventors Shahinian, Arda; Yoshinaga, Steven Kiyoshi; Senaldi, Giorgio; Bladt, Anna Tafuri; Mak, Tak Wah

Agent Shelston IP

Pub. Number AU-B-2002217969

PCT Pub. Number WO02/44364

Priority 09/728,420 28.11.00 US

Filing date 28 November 2001

Wipo publication date 11 June 2002

Acceptance publication date 20 December 2007

A01K 67/027 (2006.01) Rearing or breeding animals, not otherwise provided for - New breeds of vertebrates

A61K 38/00 (2006.01) Medicinal preparations containing peptides

A61K 39/00 (2006.01) Medicinal preparations containing antigens or antibodies

A61K 45/00 (2006.01) Medicinal preparations containing active ingredients not provided for in groups

A61P 31/12 (2006.01) Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics

A61P 35/00 (2006.01) Antineoplastic agents

A61P 37/02 (2006.01) Drugs for immunological or allergic disorders

A61P 37/04 (2006.01) Drugs for immunological or allergic disorders

A61P 37/06 (2006.01) Drugs for immunological or allergic disorders

A61P 43/00 (2006.01) Drugs for specific purposes, not provided for in groups

C07K 14/47 (2006.01) Peptides having more than 20 amino acids

C07K 14/705 (2006.01) Peptides having more than 20 amino acids

C07K 16/18 (2006.01) Immunoglobulins, e.g. monoclonal or polyclonal antibodies - against material from animals or humans

C07K 16/28 (2006.01) Immunoglobulins, e.g. monoclonal or polyclonal antibodies

C07K 19/00 (2006.01) Hybrid peptides

C12N 1/15 (2006.01) Micro-organisms, e.g. protozoa - modified by introduction of foreign genetic material

C12N 1/19 (2006.01) Micro-organisms, e.g. protozoa - modified by introduction of foreign genetic material

C12N 1/21 (2006.01) Micro-organisms, e.g. protozoa - modified by introduction of foreign genetic material

C12N 5/10 (2006.01) Undifferentiated human, animal or plant cells, e.g. cell lines - Cells modified by introduction of foreign genetic material, e.g. virus-transformed cells

C12N 15/09 (2006.01) Mutation or genetic engineering - Recombinant DNA-technology

C12N 15/12 (2006.01) Mutation or genetic engineering - Genes encoding animal proteins

C12P 21/02 (2006.01) Preparation of peptides or proteins - having a known sequence of two or more amino acids, e.g. glutathione

C12P 21/08 (2006.01) Preparation of peptides or proteins - Monoclonal antibodies