Owner SmithKline Beecham p.l.c.

Inventors Liddle, John; Leach, Colin Andrew; Ife, Robert John; Hickey, Deirdre Mary Bernadette; Stanway, Steven James; Smith, Stephen Allen; Pinto, Ivan Leo

Agent Phillips Ormonde Fitzpatrick

Pub. Number AU-B-2002210524

PCT Pub. Number WO02/30904

Priority 0024808.8 10.10.00 GB

Filing date 5 October 2001

Wipo publication date 22 April 2002

Acceptance publication date 3 June 2004

C07D 215/36 Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems

C07D 213/68 Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

C07D 495/04 Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms

C07D 513/04 Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups , or

C07D 471/04 Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups

A61P 009/10 Drugs for disorders of the cardiovascular system

A61K 031/47 - Quinolines

C07D 401/12 Heterocyclic compounds containing two or more hetero rings

C07D 221/04 Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups

C07D 215/22 Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems

C07D 487/04 Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups