Owner Emory University

Inventors Cheng, Guangjie; Lambeth, J David

Agent FB Rice

Pub. Number AU-B-2001297756

PCT Number PCT/US01/51495

PCT Pub. Number WO2002/081703

Priority 60/249,305 16.11.00 US; 60/251,364 05.12.00 US; 60/289,172 07.05.01 US; 60/289,537 07.05.01 US

Filing date 15 November 2001

Wipo publication date 21 October 2002

Acceptance publication date 8 November 2007

C12N 15/09 (2006.01) Mutation or genetic engineering - Recombinant DNA-technology

A61K 38/44 (2006.01) Medicinal preparations containing peptides

A61K 48/00 (2006.01) Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases

A61P 9/10 (2006.01) Drugs for disorders of the cardiovascular system

A61P 35/00 (2006.01) Antineoplastic agents

A61P 43/00 (2006.01) Drugs for specific purposes, not provided for in groups

C07K 16/40 (2006.01) Immunoglobulins, e.g. monoclonal or polyclonal antibodies - against enzymes

C12N 1/15 (2006.01) Micro-organisms, e.g. protozoa - modified by introduction of foreign genetic material

C12N 1/19 (2006.01) Micro-organisms, e.g. protozoa - modified by introduction of foreign genetic material

C12N 1/21 (2006.01) Micro-organisms, e.g. protozoa - modified by introduction of foreign genetic material

C12N 5/10 (2006.01) Undifferentiated human, animal or plant cells, e.g. cell lines - Cells modified by introduction of foreign genetic material, e.g. virus-transformed cells

C12N 9/02 (2006.01) Enzymes, e.g. ligases (6.) - Oxidoreductases (1.), e.g. luciferase

C12N 9/04 (2006.01) Enzymes, e.g. ligases (6.) - acting on CHOH groups as donors, e.g. glucose oxidase, lactate dehydrogenase (1.1)

C12N 15/53 (2006.01) Mutation or genetic engineering - Oxidoreductases (1)

C12Q 1/26 (2006.01) Measuring or testing processes involving enzymes or micro-organisms - involving oxidoreductase