Expression of xenogenous (human) immunoglobulins in cloned, transgenic ungulates

Details for Australian Patent Application No. 2001297523 (hide)

Owner Kirin Beer Kabushiki Kaisha Hematech, LLC

Inventors Tomizuka, Kazuma; Kuroiwa, Yoshimi; Robl, James, M.; Osborne, Barbara, A.; Ferguson, Stacy, E.; Goldsby, Richard, A.; Ishida, Isao

Agent Griffith Hack

Pub. Number AU-B-2001297523

PCT Number PCT/US01/43128

PCT Pub. Number WO2002/070648

Priority 60/311,625 09.08.01 US; 09/714,185 17.11.00 US; 60/256,458 20.12.00 US

Filing date 16 November 2001

Wipo publication date 19 September 2002

Acceptance publication date 18 January 2007

International Classifications

C12N 5/10 (2006.01) Undifferentiated human, animal or plant cells, e.g. cell lines - Cells modified by introduction of foreign genetic material, e.g. virus-transformed cells

A01K 67/027 (2006.01) Rearing or breeding animals, not otherwise provided for - New breeds of vertebrates

C07K 14/47 (2006.01) Peptides having more than 20 amino acids

C07K 16/04 (2006.01) Immunoglobulins, e.g. monoclonal or polyclonal antibodies - from milk

C07K 16/18 (2006.01) Immunoglobulins, e.g. monoclonal or polyclonal antibodies - against material from animals or humans

C12N 9/10 (2006.01) Enzymes, e.g. ligases (6.) - Transferases (2.)

C12N 15/02 (2006.01) Mutation or genetic engineering - Preparation of hybrid cells by fusion of two or more cells, e.g. protoplast fusion

C12N 15/09 (2006.01) Mutation or genetic engineering - Recombinant DNA-technology

C12N 15/85 (2006.01) Mutation or genetic engineering - for animal cells

C12P 21/08 (2006.01) Preparation of peptides or proteins - Monoclonal antibodies

Event Publications

12 December 2002 Complete Application Filed

  Priority application(s): 60/311,625 09.08.01 US; 09/714,185 17.11.00 US; 60/256,458 20.12.00 US

13 March 2003 Application Open to Public Inspection

  Published as AU-B-2001297523

21 October 2004 Amendment Made

  The nature of the amendment is: Add co-inventor Osborne, Barbara, A. 2002

18 January 2007 Application Accepted

  Published as AU-B-2001297523

17 May 2007 Standard Patent Sealed

14 August 2008 Assignment Registered

  Kirin Beer Kabushiki Kaisha; Hematech, LLC The patent has been assigned to Kirin Pharma Kabushiki Kaisha

26 March 2009 Assignment Registered

  Kirin Pharma Kabushiki Kaisha The patent has been assigned to Kyowa Hakko Kirin Co., Ltd.

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