Owner Chiron Corporation

Inventors Polo, John M; Barnett, Susan; Donnelly, John James; O'Hagan, Derek; Dubensky Jr., Thomas W.; Ulmer, Jeffrey; Otten, Gillis; Singh, Manmohan

Agent FB Rice

Pub. Number AU-B-2001294897

PCT Pub. Number WO02/26209

Priority 60/315,905 30.08.01 US; 60/236,105 28.09.00 US

Filing date 28 September 2001

Wipo publication date 8 April 2002

Acceptance publication date 19 April 2007

C12N 15/09 (2006.01) Mutation or genetic engineering - Recombinant DNA-technology

A61K 9/00 (2006.01) Medicinal preparations characterised by special physical form

A61K 9/16 (2006.01) Medicinal preparations characterised by special physical form - Agglomerates

A61K 9/51 (2006.01) Medicinal preparations characterised by special physical form - Nanocapsules

A61K 35/76 (2006.01) Medicinal preparations containing material or reaction products thereof with undetermined constitution

A61K 38/00 (2006.01) Medicinal preparations containing peptides

A61K 39/00 (2006.01) Medicinal preparations containing antigens or antibodies

A61K 39/145 (2006.01) Medicinal preparations containing antigens or antibodies - Orthomyxoviridae, e.g. influenza virus

A61K 39/21 (2006.01) Medicinal preparations containing antigens or antibodies - Retroviridae, e.g. equine infectious anemia virus

A61K 39/29 (2006.01) Medicinal preparations containing antigens or antibodies - Hepatitis virus

A61K 39/39 (2006.01) Medicinal preparations containing antigens or antibodies - characterised by the immunostimulating additives, e.g. chemical adjuvants

A61K 45/00 (2006.01) Medicinal preparations containing active ingredients not provided for in groups

A61K 47/06 (2006.01) Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives - Organic compounds

A61K 47/14 (2006.01) Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives - Esters of carboxylic acids

A61K 47/16 (2006.01) Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives - containing nitrogen

A61K 47/32 (2006.01) Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives - Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds

A61K 47/34 (2006.01) Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives - Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds

A61K 47/46 (2006.01) Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives - Ingredients of undetermined constitution or reaction products thereof

A61K 47/48 (2006.01) Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives - the non-active ingredient being chemically bound to the active ingredient, e.g. polymer drug conjugates

A61K 48/00 (2006.01) Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases

A61P 31/04 (2006.01) Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics

A61P 31/12 (2006.01) Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics

A61P 33/00 (2006.01) Antiparasitic agents

A61P 37/04 (2006.01) Drugs for immunological or allergic disorders