Owner Genentech, Inc.

Inventors Gerritsen, Mary E.; Sliwkowski, Mark X.

Agent Griffith Hack

Pub. Number AU-B-2001286918

PCT Pub. Number WO02/18444

Priority 60/265,516 31.01.01 US; 09/940,101 27.08.01 US; 60/229,679 01.09.00 US

Filing date 29 August 2001

Wipo publication date 13 March 2002

Acceptance publication date 21 December 2006

G01N 33/50 (2006.01) Investigating or analysing materials by specific methods not covered by groups - Chemical analysis of biological material, e.g. blood, urine

A61K 38/00 (2006.01) Medicinal preparations containing peptides

A61K 39/395 (2006.01) Medicinal preparations containing antigens or antibodies - Antibodies

A61K 45/00 (2006.01) Medicinal preparations containing active ingredients not provided for in groups

A61K 48/00 (2006.01) Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases

A61P 9/00 (2006.01) Drugs for disorders of the cardiovascular system

A61P 9/12 (2006.01) Drugs for disorders of the cardiovascular system

A61P 13/10 (2006.01) Drugs for disorders of the urinary system

A61P 21/00 (2006.01) Drugs for disorders of the muscular or neuromuscular system

C07K 14/475 (2006.01) Peptides having more than 20 amino acids

C07K 16/40 (2006.01) Immunoglobulins, e.g. monoclonal or polyclonal antibodies - against enzymes

C12N 15/02 (2006.01) Mutation or genetic engineering - Preparation of hybrid cells by fusion of two or more cells, e.g. protoplast fusion

C12P 21/08 (2006.01) Preparation of peptides or proteins - Monoclonal antibodies

G01N 33/15 (2006.01) Investigating or analysing materials by specific methods not covered by groups - Medicinal preparations

G01N 33/53 (2006.01) Investigating or analysing materials by specific methods not covered by groups - Immunoassay

G01N 33/566 (2006.01) Investigating or analysing materials by specific methods not covered by groups - using specific carrier or receptor proteins as ligand binding reagent